The Absorption of Glucose from the Small Intestine in Deficiency Disease

Glucose and fructose absorption in idiopathic steatorrhoea.

“…On the few occasions on which this has been done, by using intestinal intubation, glucose absorption has been found to be only a fraction of that in normal persons (Groen, 1938;Fordtran, Levitan, Bickerman, Burrows, and Ingelfinger, 1961; Schedl and Clifton, 1961) but not to correlate with the degree of flattening of the glucose tolerance curves on the same patients (Taylor and Wightman, 1952). Fructose absorption has not been directly studied in idiopathic steatorrhoea, although it has been claimed on the basis of blood tolerance tests that fructose absorption is unaffected, while glucose absorption is defective (Maegraith, Adams, Havard, King, and Millet, 1945).…”

Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia. Viii. Further Studies of the Proteolytic Activity of Normal Human Gastric Juice in Vitro; And the Limitations of the Method in Pernicious Anemia 1

“…of gastric contents derived from pernicious anemia patients were given daily with 200 grams of beef muscle, moderate effects on blood production in another patient with pernicious anemia were observed. Accordingly, in explaining the development of any one case of macrocytic anemia responsive to treatment with liver extract, account must be taken not only of variations in the amount of intrinsic factor but also in the amount of extrinsic factor ingested (4,13,14), of difficulty with intestinal absorption (4,15), and possibly of positive or toxic factors of in.testinal origin (16,17). For this reason, any test applied to gastric secretion alone cannot be expected to be of absolute diagnostic significance.…”

Gastrointestinal Absorption with Oleic Acid-I131 and L-Methionine-S35 in Patients with Ulcerative Colitis.

“…Several studies have been reported pointing to possible impairment of small bowel absorption in patients with ulcerative colitis (1)(2)(3)(4)(5). These studies employed the closed intestinal loop technic or tolerance tests, or dealt with percentage loss of nitrogen in the ileal discharge.…”