2017
DOI: 10.1186/s13071-017-2534-5
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The acaricidal speed of kill of orally administered fluralaner against poultry red mites (Dermanyssus gallinae) on laying hens and its impact on mite reproduction

Abstract: Background Dermanyssus gallinae, the poultry red mite, is a growing threat to chickens in poultry farms. This nocturnal hematophagous ectoparasite has a rapid rate of proliferation with a negative impact on the birds’ health, welfare and productivity resulting in severe economic consequences for poultry farmers. A study was performed with fluralaner, a novel systemic ectoparasiticide, to evaluate its effect on mite vitality and reproduction after oral administration to laying hens.MethodsSixteen healthy hens w… Show more

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Cited by 29 publications
(29 citation statements)
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“…Fluralaner has high activity towards parasitic mites on animals, such as demodectic mite ( Demodex sp.) on Shih‐Tzu Canis lupus dingo Meyer and red‐handed tamarins Saguinus midas , poultry red mite Dermanyssus gallinae in birds, and northern fowl mite Ornithonyssus sylviarum in laying hens . In addition, fluralaner also exhibits high activity towards the phytophagous mite of TSSM and has been shown to bring about 100% mortality at a concentration of 3.1 mg L −1 against fipronil‐resistant (∼ 500 mg L −1 ) TSSM …”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Fluralaner has high activity towards parasitic mites on animals, such as demodectic mite ( Demodex sp.) on Shih‐Tzu Canis lupus dingo Meyer and red‐handed tamarins Saguinus midas , poultry red mite Dermanyssus gallinae in birds, and northern fowl mite Ornithonyssus sylviarum in laying hens . In addition, fluralaner also exhibits high activity towards the phytophagous mite of TSSM and has been shown to bring about 100% mortality at a concentration of 3.1 mg L −1 against fipronil‐resistant (∼ 500 mg L −1 ) TSSM …”
Section: Introductionmentioning
confidence: 99%
“…on Shih-Tzu Canis lupus dingo Meyer 18 and red-handed tamarins Saguinus midas, 19 poultry red mite Dermanyssus gallinae in birds, 20 and northern fowl mite Ornithonyssus sylviarum in laying hens. [21][22][23] In addition, fluralaner also exhibits high activity towards the phytophagous mite of TSSM and has been shown to bring about 100% mortality at a concentration of 3.1 mg L −1 against fipronil-resistant (∼ 500 mg L −1 ) TSSM. 24 As is well-known, research on the toxicological effects of fluralaner towards TSSM will enhance the ability to design and execute mite management programs.…”
Section: Introductionmentioning
confidence: 99%
“…Prior evidence that the isoxazolines would be effective against lice was reported in a study of dogs naturally infested with the sucking louse Linognathus setosus . Several prior studies that used isoxazolines in poultry also supported the potential efficacy and safety of an isoxazoline against ectoparasites on birds …”
Section: Discussionmentioning
confidence: 95%
“…Afoxolaner (NexGard ® , Merial; Lyon, France) is an antiparasitic drug in the class of isoxazolines . The mechanism of action of the isoxazolines is inhibition of chloride channels dependent on glutamate and gamma‐aminobutyric acid (GABA) . Drugs in this class have been used successfully in exotic animals for the treatment of a variety of insect and mite infestations .…”
Section: Introductionmentioning
confidence: 99%
“…To identify performance parameters that were impacted by the PRM infestations, it was intended to examine changes in performance after implementing a highly effective treatment to the hens. For the latter , fluralaner (Exzolt®, MSD Animal Health) was administered through the drinking water twice with a 7-day interval at a dose of 0.5 mg/kg, providing the chickens with effective blood levels for approximately 2 weeks (Brauneis et al, 2017). Fluralaner was administered in the infested as well as in the non-infested units, all at the same time.…”
Section: Methodsmentioning
confidence: 99%