The acceptance of illness, the intensity of pain and the quality of life in patients with lung cancer

Chabowski, Mariusz; Polański, Jacek; Jankowska-Polańska, Beata; Lomper, Katarzyna; Janczak, Dariusz; Rosińczuk, Joanna

doi:10.21037/jtd.2017.08.70

Cited by 48 publications

(43 citation statements)

References 24 publications

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“…In his studies analysing diabetic patients, males after myocardial infarction, males with chronic pain, and females diagnosed with migraine scored 24.82, 22.14, 18.46, and 24.23 points, respectively. In patients with malignancies, breast, uterine prostate, and colon cancer patients showed similar levels of acceptance of illness comparing to our population [ 7 , 24 , 33 , 45 , 52 , 53 ].…”

Section: Discussionsupporting

confidence: 53%

Assessment of Pain Management, Acceptance of Illness, and Adjustment to Life with Cancer in Patients with Nonmuscle Invasive Bladder Cancer

Krajewski

Mazur

Poterek

et al. 2018

BioMed Research International

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Purpose According to the European Association of Urology bladder cancer is the seventh most commonly diagnosed malignancy in the world's male population. Despite its high incidence, papers evaluating psychological state in those patients' group are lacking. The purpose of the study was to evaluate pain management, disease acceptance, and adjustment to cancer in homogenous group of patients diagnosed with nonmuscle-invasive bladder cancer (NMIBC). Methods Group of 252 male patients who were scheduled for NMIBC treatment were prospectively evaluated. Patients fulfilled Acceptance of Illness Scale (AIS), Mini-Mental Adjustment to Cancer (Mini-MAC) and Coping Strategies (CSQ) questionnaires before treatment introduction. Results Highest CSQ score was achieved by the coping self-statements subscale (mean=18,37). The catastrophizing subscale score was the lowest (mean=11,24). Place of residence affected results of CSQ statement about pain control. Catastrophizing and coping self-statements strategies were associated with matrimonial status. In the Mini-MAC questionnaire the fighting spirit way of coping had the highest (21,73) and the helplessness-hopelessness subscale had the lowest mean value (13,3). Matrimonial status was strongly associated with anxious preoccupation, fighting spirit, and helplessness – hopelessness way of coping. The mean AIS test score was 28.8. AIS result was influenced by patient's marital status, yet not by education, place of residence, nor any clinical factor. Conclusions In the examined group, the level of acceptance of the disease reached values that were slightly higher than the average. It indicated a fairly good adaptation to cancer. Among the methods of coping with cancer, the constructive style is definitely dominant with a high intensity of the fighting spirit strategy. The destructive style of cancer coping reached low values with a low intensity of helplessness/hopelessness strategy. From pain coping strategies, self-statements and praying/hoping were the most commonly chosen ways, whereas catastrophizing was the rarest. Many associations between various questioners' results were also observed.

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Section: Discussionsupporting

confidence: 53%

Assessment of Pain Management, Acceptance of Illness, and Adjustment to Life with Cancer in Patients with Nonmuscle Invasive Bladder Cancer

Krajewski

Mazur

Poterek

et al. 2018

BioMed Research International

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“…7 Illness acceptance had a positive impact on the studied women's QoL, which is consistent with literature data. 39 Greater illness acceptance reduced the intensity of symptoms such as pain or diarrhoea, but was also associated with better sexual function, better body image, increased sexual satisfaction, and improved financial standing. In the correlation analysis, pain had a negative impact on QoL and illness acceptance.…”

Section: Discussionmentioning

confidence: 98%

<p>The Association Between Illness Acceptance and Quality of Life in Women with Breast Cancer</p>

Jankowska‐Polańska¹,

Świątoniowska-Lonc²,

Ośmiałowska³

et al. 2020

CMAR

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Introduction: Breast cancer is the most common cause of cancer death in women. Aim: The aim of the study was to investigate the association between illness acceptance and quality of life (QoL) in patients with breast cancer. Patients and Methods: The study included 150 patients who had undergone surgery for breast cancer. The following standardized questionnaires were used: the Acceptance of Illness Scale (AIS), the EORT QLQ-C30 (The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30), and the EORT QL-BR 23 (Quality of Life Questionnaire for Breast Cancer) for QoL evaluation. Socio-clinical data were obtained from the patients' medical records. Results: In the study group, the overall QoL score was 62.67±17.11 in the BCT group, 63 ±14.3 in the MTX group, and the highest: 65.5±20.2 in the reconstruction group. Comparative analysis showed that patients in the BCT group reported significantly more fatigue (p=0.007) and appetite loss (p=0.032) than those in the MTX+R group. Patients in the MTX group were significantly less satisfied with their body image (p=0.001) and experienced more financial troubles (p=0.013) than the remaining patients. Patients in the MTX+R group reported significantly better sexual function and more sexual enjoyment than the remaining patients (p<0.001). All patients scored high for illness acceptance, though patients in the MTX group had lower scores (28.17±7.2) than the others: 31.84±6.51 in the BCT group and 32.78±7.97 in the MTX+R group. The comparative analysis of QoL according to the level of AIS showed the significantly better QoL and less intense symptoms within all the domains except for the insomnia and hair loss domains in the group of high AIS in comparison with medium and lack of AIS. Acceptance of illness significantly correlated with 4 domains of the QLQ-C30 (p<0.05). The correlation between illness acceptance and overall QoL was positive (r=0.243; p=0.003)-the higher the acceptance, the better the QoL. Correlations with pain, diarrhoea, and financial difficulties were negative. Illness acceptance was positively correlated with QoL in 3 domains of the EORTC-BR23: body image (p<0.001), sexual function (p=0.015), and sexual enjoyment (p=0.047), and negatively with the "treatment side effects" (p=0.011). Conclusion: The level of illness acceptance varies depending on the treatment method, and is the lowest in the group of women having undergone a mastectomy, and the highest in patients after a mastectomy with immediate breast reconstruction. Acceptance of illness improves the QoL of women treated for breast cancer, regardless of the specific treatment method.

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“…Among the types of diagnosed lung cancers, non-small cell lung cancer (NSCLC) accounts for ~80% (4). Despite advances in treatment, the 5-year survival rate of patients with lung cancer is still <15% (5). The presence of local recurrence of tumors and distant metastasis may be the most common cause of death (6).…”

Section: Introductionmentioning

confidence: 99%

BATF acts as an oncogene in non‑small cell lung cancer

Pan

Zhang

et al. 2019

Oncol Lett

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One of the main causes of cancer incidence and mortality worldwide is lung cancer. This study focused on the function of basic leucine zipper ATF-like transcription factor (BATF) in non-small cell lung cancer (NSCLC). Using NSCLC patient data from The Cancer Genome Atlas, the present study demonstrated that BATF expression in NSCLC tissues was significantly higher compared with that in adjacent non-tumor tissues (P=6.56x10-6). Lentivirus-mediated short hairpin RNA (shRNA) was used to knock down BATF expression in the human A549 NSCLC cell line and assessed by reverse transcription-quantitative PCR and western blotting. Cell proliferation was evaluated by MTT assay and Celigo imaging cytometry. Apoptosis was detected by fluorescence-activated cell sorting and caspase 3/7 activity analysis. The results revealed that knockdown of BATF inhibited the proliferation of A549 cells. Compared with that of the control group, the apoptosis rate of the BATF-shRNA group was significantly higher. In summary, knockdown of BATF inhibited the proliferation of A549 cells and promoted apoptosis. These results provide important information about the underlying mechanism of the pathogenesis of NSCLC.

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The acceptance of illness, the intensity of pain and the quality of life in patients with lung cancer

Cited by 48 publications

References 24 publications

Assessment of Pain Management, Acceptance of Illness, and Adjustment to Life with Cancer in Patients with Nonmuscle Invasive Bladder Cancer

Assessment of Pain Management, Acceptance of Illness, and Adjustment to Life with Cancer in Patients with Nonmuscle Invasive Bladder Cancer

<p>The Association Between Illness Acceptance and Quality of Life in Women with Breast Cancer</p>

BATF acts as an oncogene in non‑small cell lung cancer

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