The acoustic cortex in vascular dementia: a Golgi and electron microscope study

Baloyannis, Stavros J.

doi:10.1016/j.jns.2004.11.025

Cited by 6 publications

(4 citation statements)

References 23 publications

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“…Even in the 21st century, quantitative analysis of Golgiimpregnated neurons can provide information on the dendritic organization of auditory and other central nervous system nuclei (e.g., Winer and Prieto, 2001;Cetas et al, 2002;Lorke et al, 2003;Kulesza, 2007;Baloyannis, 2005;Baloyannis et al, 2009;Bose et al, 2010). However, when used as a basis for quantitative analysis, the classical Golgi method (Golgi, 1873) is hampered by several technical problems.…”

Section: Methodological Considerations and Technical Limitationsmentioning

confidence: 99%

Computer-assisted 3-D reconstructions of Golgi-impregnated neurons in the cortical regions of the inferior colliculus of rat

2011

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Section: Methodological Considerations and Technical Limitationsmentioning

confidence: 99%

Computer-assisted 3-D reconstructions of Golgi-impregnated neurons in the cortical regions of the inferior colliculus of rat

2011

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“…Though auditory dysfunction is rarely the presenting feature, histopathological involvement of auditory cortices has been described in major neurodegenerative dementias [ 26 , 38 – 41 ], and deficits of auditory cognition (Table 1 ) are not uncommon early features of these diseases. Certain general observations suggest an auditory cognitive disorder: the patient typically experiences greater listening difficulties and derives less benefit with conventional binaural amplification than anticipated from the degree of audiometric loss and may also exhibit various abnormal behavioural responses to sounds.…”

Section: Symptoms Of Altered Auditory Cognition In Dementiamentioning

confidence: 99%

Hearing and dementia

et al. 2016

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Hearing deficits associated with cognitive impairment have attracted much recent interest, motivated by emerging evidence that impaired hearing is a risk factor for cognitive decline. However, dementia and hearing impairment present immense challenges in their own right, and their intersection in the auditory brain remains poorly understood and difficult to assess. Here, we outline a clinically oriented, symptom-based approach to the assessment of hearing in dementias, informed by recent progress in the clinical auditory neuroscience of these diseases. We consider the significance and interpretation of hearing loss and symptoms that point to a disorder of auditory cognition in patients with dementia. We identify key auditory characteristics of some important dementias and conclude with a bedside approach to assessing and managing auditory dysfunction in dementia.

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“…The majority of the synapses demonstrate changes in size and shape of the pre-and postsynaptic components as well as alterations of the mitochondria (Baloyannis, 2005(Baloyannis, , 2006. Further investigations concerning the interaction of ApoE and mitochondrial DNA, suggested that this interaction is restricted to AD and may affect susceptibility to the disease (Carrieri et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

Apolipoprotein E Phenotype in Demented Patients in Greek Population

Hatzifilippou

Banaki

Τράκα

et al. 2008

International Journal of Neuroscience

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Apolipoprotein E is a plasma protein, involved in the transport of lipids and their metabolism. The aim of this investigation was to correlate the ApoE phenotypes with the type and the severity of dementia in Greek demented patients. The investigation revealed that 72% of the patients have the E3/3 phenotype, but only 11% of them demonstrated the E3/2; 13% of the patients have the E4/3 phenotype and only 4% of them demonstrated the phenotype E4/4. The most severely demented patients corresponded to e4 alléle. The present results indicate that the most common ApoE phenotype in Greek demented patients is E3/3.

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The acoustic cortex in vascular dementia: a Golgi and electron microscope study

Cited by 6 publications

References 23 publications

Computer-assisted 3-D reconstructions of Golgi-impregnated neurons in the cortical regions of the inferior colliculus of rat

Computer-assisted 3-D reconstructions of Golgi-impregnated neurons in the cortical regions of the inferior colliculus of rat

Hearing and dementia

Apolipoprotein E Phenotype in Demented Patients in Greek Population

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