The active site of human Tyrosinase-related Protein: can it be inhibited by plants?

Falya, Yuniarti; Firmansyah, Deni; Saptarini, Nyi Mekar; Andriani, Yuli; Sumiwi, Sri Adi; Levita, Jutti

doi:10.51847/oa8f56q

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…Even though there are some successfully adopted fish and rice integrated farming system techniques in Asian continent countries, like India and China, the concept of agricultural-based pairing up, and a systematic combination of cultivation, aquaculture, and animal husbandry is still not widely used in these areas and yet to educate people (The paddy-field wetland is ideal for breeding and feeding a variety of fish (Figure 1). Most spawnings in rice fields produce glue-like eggs that are generally arranged on green plants to provide extra oxygen and nutrition designed for maturing embryos (AL-Kattan et al, 2019;Al-Rejaboo & Jalaluldeen, 2019;Falya et al, 2021). However, shallow water net constructors and spawners breed in paddy fields under ideal conditions) (Paramesh et al, 2022).…”

Section: Objectives Of Integrated Farmingmentioning

confidence: 99%

A Sustainable Way for Integrated Farming System: A Case Study on Bellary District of Karnataka, India

Holachi¹,

Sathyanarayanaroa²,

Achar³

et al. 2023

World J Environ Biosci

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Sustainable development is a concept that strives to gain economic progress and to make developments in agriculture that stays for long without harming the environment. while conserving the soil biodiversity and environmental prolonged value. It also serves as a framework for integrating environmental regulations with development initiatives. Recently, there has been a pressing need to embrace greater sustainable farming methods, and a logical evaluation method is required to identify innovative management options. One kind of environmentally-friendly farming that has recently emerged is the integrated crop-livestock farming system. The importance of an integrated farm and livestock system for sustainable development, and the fact that integrated crop and livestock systems have been a foundation of agriculture for hundreds of years, imply a diverse range of integrated ecological, biophysical, and socioeconomic conditions. Sometimes it is difficult to maintain sustainable agriculture in dry areas like Bellary. Adopting an appropriate integrated agricultural system model is very important to achieve sustainability in lowland rice cultivation in the Tungabhadra project located in Karnataka. Continued rice cultivation and practice in the region have resulted in resource deprivation and condensed and decreased yields. The diminution of hereditary soil assets, the development of nuisance and pests scenarios like brown plant hopper, and the problem of weeds were also noticed.

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Section: Objectives Of Integrated Farmingmentioning

confidence: 99%

A Sustainable Way for Integrated Farming System: A Case Study on Bellary District of Karnataka, India

Holachi¹,

Sathyanarayanaroa²,

Achar³

et al. 2023

World J Environ Biosci

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“…Hydroquinone interacts with Bacillus megaterium tyrosinase by forming two hydrogen bonds with Asn205 and Pro219, two hydrophobic contacts with Ala221 and Val218, and one pi-pi interaction with His208. Hydroquinone can act as a substrate for Bacillus megaterium and a tyrosinase inhibitor [6].…”

Section: Introductionmentioning

confidence: 99%

“…The flavonoid compounds contained in Morus sp. are reported to have a structure-activity relationship on the glucoside, stilbene, and glucoside, 2-arylbenzofuran derivatives, where the resorcinol group is not substituted in the 2'-and 4'-OH in ring B so that it plays a role in tyrosinase inhibition [6]. However, the bonding mode between the compounds contained in the leaf extract of Morus sp.…”

Section: Introductionmentioning

confidence: 99%

Discovering Tyrosinase Inhibitors From Morus Sp. Plants: An in Silico Study

Falya

AMELIA²,

RIZIKIYAN³

et al. 2022

Int J App Pharm

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Objective: This study aimed to examine Morus sp. compounds bonding mode with critical amino acid residues in the binding pocket of the enzyme TRP1 in In silico so that it can be used as a support in the design of skin-lightening cosmetics based on Morus sp. Methods: Docking is done using autodock tools software, chem office 2019, ChemDraw professional 12, autodock 4.2, discovery studio 2016. Results: Isorhamnetin has two hydrogen bonds to amino acids Met215 and Asn205. Other compounds found in Morus sp., which have hydrogen bonds with Asn205, are dihydromorin, kaempferol, quercitrin, rutin, and morusin. Conclusion: Isorhamnetin has the best potential among other compounds as a tyrosinase inhibitor by hydrogen binding to the amino acid Met215, and Asn205 has a free energy of-6.16 kcal/mol.

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Anticancer activity of Lannea coromandelica on B16F10 melanoma cell line: an in vitro and molecular docking approach

Nargatti,

Wadkar

2024

Journal of Herbal Medicine

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The active site of human Tyrosinase-related Protein: can it be inhibited by plants?

Cited by 3 publications

References 24 publications

A Sustainable Way for Integrated Farming System: A Case Study on Bellary District of Karnataka, India

A Sustainable Way for Integrated Farming System: A Case Study on Bellary District of Karnataka, India

Discovering Tyrosinase Inhibitors From Morus Sp. Plants: An in Silico Study

Anticancer activity of Lannea coromandelica on B16F10 melanoma cell line: an in vitro and molecular docking approach

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