2015
DOI: 10.15406/jnsk.2015.03.00111
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The Acute Effect Of The Antioxidant Drug “U-74389g” On Platelet Distribution Width During Hypoxia Reoxygenation Injury In Rats

Abstract: Background: Platelet activation causes morphologic changes of platelets, including both the spherical shape and pseudopodia formation increasing platelet distribution width (PDW), ascribed to platelet anisocytosis. Furthermore, coagulation is activated in vaso-occlusive situations, increasing PDW. Early diagnosis of progressive activation of coagulation or any factor declining PDW levels, can prevent these thromboembolic diseases successfully. The probable beneficial effect of the molecule "U-74389" was studie… Show more

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Cited by 8 publications
(13 citation statements)
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“…The effect of the antioxidant drug U-74389G on urea levels during ischemia reperfusion injury in rats N o n -c o m m e r c i a l u s e o n l y [3][4][5][6][7] oxygen supply, electrocardiogram and acidometry. Post-experimental awakening and preservation of animals were not permitted, even if euthanasia was needed.…”
Section: This Basic Experimental Research Was Licensed Bymentioning
confidence: 99%
“…The effect of the antioxidant drug U-74389G on urea levels during ischemia reperfusion injury in rats N o n -c o m m e r c i a l u s e o n l y [3][4][5][6][7] oxygen supply, electrocardiogram and acidometry. Post-experimental awakening and preservation of animals were not permitted, even if euthanasia was needed.…”
Section: This Basic Experimental Research Was Licensed Bymentioning
confidence: 99%
“…Ad libitum diet accompanied the 7 days pre-experimental normal housing in laboratory. Prenarcosis engaged the nonstop intra-experimental care including general anesthesia [3][4][5][6], oxygen supply, electrocardiogram and acidometry. Post-experimental euthanasia excluded awakening and preservation of the animals.…”
Section: Animal Preparationmentioning
confidence: 99%
“…7 days pre-experimental normal housing included ad libitum diet in laboratory. Prenarcosis of animals preceded of continuous intra-experimental general anesthesia [3][4][5][6], oxygen supply, electrocardiogram and acidometry. Post-experimental euthanasia did not permitted awakening and preservation of the animals.…”
Section: Animal Preparationmentioning
confidence: 99%