The Adjuvant Role of Alginate on Antibody Response to Ragweed Extracts in the Rabbit

Functional Activities of γG Ragweed Antibodies Isolated by an Immunospecific Method

“…Sensitivities of indirect haemagglutination techniques are reported to be approxima tely 0.005 fig Ab N/ml [10] while the tannic acid method permitted the detection of 0.003-0.006 fig Ab N [11,12]. Pool C (0-60), a purified extract obtained from small ragweed pollen [13,14] which was used in the present study to coat the tanned red cells, has been shown to be an effective agent for this purpose [15,16,17]. Other ragweed extracts, which differed in heterogeneity and allergenic activity, were similarly used for haemagglutination, but in each case the haemagglutination titer of a given sample of RPAb was diminished relative to Pool C (0-60).…”