The Adrenal Cortex and Homeostasis

Sayers, George

doi:10.1152/physrev.1950.30.3.241

Cited by 399 publications

(83 citation statements)

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“…One recent reviewer (Sayers, 1950) Doubtless the steroid hormones of the adrenal cortex are necessary for many homoeostatic adjustments in mammals. However, it appears that there is a distinct possibility that many mammals possess well-adjusted homoeostatic mechanisms which are 'set' to take care of most, if not all, emergencies without resorting to large fluctuations in adrenal steroid production and certainly without metabolic depletion of the organ.…”

Section: Discussionmentioning

confidence: 99%

The effects of acute stress and of ACTH upon ascorbic acid and lipid content of the adrenal glands of wild rats

Woods¹

1957

The Journal of Physiology

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Section: Discussionmentioning

confidence: 99%

The effects of acute stress and of ACTH upon ascorbic acid and lipid content of the adrenal glands of wild rats

Woods¹

1957

The Journal of Physiology

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“…12 ( Sayers et al , 1950) . In the present study Lipid depletion is seen in ZF in 90% cases which corroborates with the findings of Howe EE (2000), 7 Kare M (1969) , 8 In 70% of the cases there is presence of prominent sinusoids which reflects the further vascular demand for the increased endocrine activities of adrenal in adaptation to new challenges to stress which corroborates with the findings of Howe EE (2000) 7 .…”

Section: IIImentioning

confidence: 99%

Histological Study of Adrenal Gland In Case Of Suicidal Deaths

Patra¹,

Rath²,

Dutta³

et al. 2014

IOSRJDMS

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Material for study -Right and Left adrenal . No. of Suicidal cases -HundredNo. of Accidental cases (control)-Twenty . Results: On Histological study it was found that the cells in Zona Glomerulosa showed increased nuclear density. Hypertrophy and hyperplasia of Zona Fasciculata with intracytoplasmic lipid depletion varying from mild to extensive giving rise to parenchymal cord-like arrangement of cells .Sinusoidal prominence in all the three zones including medulla.A normal pattern of Adrenal gland is informative of receipt of sudden violence i.e accident. Conclusion: The present study concludes and supports the idea that chronic stress as in suicide usuallyinduces adrenal growth which may have implications for forensic people in revealing the cause of unknown deaths.

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“…Depletion of adrenal ascorbic acid and cholesterol occurs in rats, guinea pigs and chickens after pituitary adrenotropic hormone injection and following stressful conditions as a result of the increase in adrenocortical activity (14,27).…”

Section: Resultsmentioning

confidence: 99%

The effect of furazolidone on some clinical and biochemical parameters in goats

Mustafa

Ali

Hassan

1986

Veterinary Quarterly

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SUMMARY Furazolidone (FZ) administered to goats orally at the recommended therapeutic dose (10 mg/kg body weight for 5 days) resulted in significant decreases in heart rate, pulse rate, and rectal temperature. No change was observed in respiratory rate or body weight, although a tendency towards a decrease in the latter was observed. An increase in the number of the erythrocytes was found. FZ also produced significant decreases in the pseudocholinesterase activity and plasma concentrations of total protein and ascorbic acid. A significant increase in the adrenal cholesterol concentration was observed while the weight of adrenal glands and their ascorbic acid concentration and content were unaffected. No significant histopathological changes were observed in treated goats.

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The Adrenal Cortex and Homeostasis

Cited by 399 publications

References 0 publications

The effects of acute stress and of ACTH upon ascorbic acid and lipid content of the adrenal glands of wild rats

The effects of acute stress and of ACTH upon ascorbic acid and lipid content of the adrenal glands of wild rats

Histological Study of Adrenal Gland In Case Of Suicidal Deaths

The effect of furazolidone on some clinical and biochemical parameters in goats

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