The Advances of Carbon Nanotubes in Cancer Diagnostics and Therapeutics

Abstract

Carbon nanotubes (CNTs), one of the unique one-dimensional nanomaterials, have gained great attention because of their specific characters, versatile functionalization chemistry, and biological compatibility in the past few decades. CNTs can be functionalized via different methods to perform their specific functions. CNTs have been used in various areas of biomedicine as nanocarriers, including cancer diagnosis and therapy. Different molecules such as peptide, antigen, and nucleic acid can be delivered to cancer cells by CNTs with high efficiency. In this review, we summarized the properties of CNTs and the method of CNTs functionalization and illustrated their application in cancer diagnosis and therapy.

Nanotechnology platforms for cancer immunotherapy

“…Over the past few decades, many nanoparticles‐based delivery systems have been developed and employed in clinical diagnosis and therapy (Z. Chen et al, ; Z. Chen et al, ; Ma et al, ; Pan et al, ; Z. Yang et al, ; C. Zhou, Yang, & Teng, ). For cancer immunotherapy, nanoparticle‐based platforms can be divided into two types according to the substrate component: naturally derived nanoparticles and synthetic nanoparticles.…”

Development of hydrophobic reduced graphene oxide as a new efficient approach for photochemotherapy

“…Recently, nanoparticles with functionalised carbon family networks have shown great promise for cancer targeting and drug delivery in specic chemotherapy treatments, such as carbon dots, carbon nanotubes (CNTs), fullerenes, and graphene materials. [11][12][13][14][15][16] Among these carbon nanomaterials, graphene is the most suitable and commonly used material in a variety of applications due to its sheet exibility. It is capable of generating heat by alternating the magnetic eld or through lasers of noble metals.…”

Carbon Nanomaterials for Breast Cancer Treatment

“…However, carbon nanomaterials have some disadvantages including their lack of solubility and low reproduction rate through their chemical functionalization and structural characterization. Furthermore, their use in medicine is widely tested due to their potential toxicity [32][33][34][35][36][37][38][39].…”

“…CNTs are particularly of scientific interest due to their chemical stability, mechanic resistance, high electrical and thermal conductivity, high surface area, and tubular structure, as well as their ability to pass through the membranes of endothelial, vascular, and tumor cells [32,38,[42][43][44]. The surface and high electrical and thermal conductivity of CNTs allow other molecules (drugs, peptides, and nucleic acids) to be attached to their walls and extremities.…”