The advantage of antenatal diagnosis of intestinal and urinary tract malformations

Kullendorff, Carl‐Magnus; Larsson, Linda; Jörgensen, Connie

doi:10.1111/j.1471-0528.1984.tb05898.x

Cited by 24 publications

(6 citation statements)

References 10 publications

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“…Many of the genitourinary tract anomalies are already detected in the screening weeks but the detection rate for urinary tract anomalies increases with fetal age [9,13]. In our study the cases of fetal hydronephrosis that normalized represented physiological grade I [5] dilatation.…”

Section: Discussionmentioning

confidence: 68%

Fetal anomalies in a controlled one-stage ultrasound screening trial. A report from the Helsinki Ultrasound Trial

Saari-Kemppainen¹,

Karjalainen²,

Ylöstalo³

et al. 1994

Jpme

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The aim of the study was to compare whether systematic strictly timed screening of all pregnancies would improve the detection of major fetal anomalies. All pregnant women (95%) from a certain area were randomly allocated for one ultrasound screening examination between the 16th and 20th weeks of gestation. Otherwise the screening (N = 4691) and control groups (N = 4619) received the same antenatal care. Screening included a systematic search for fetal anomalies. In the screening group, 40% of major fetal anomalies were detected in the screening, and 11 abortions were induced because the malformation was either lethal or severely handicapping. In the control group, 77.0% of participants had ultrasound examination any time during pregnancy. By ultrasound 13 (27%) major fetal anomalies were detected, only two of these before the 21st week of gestation. Screening detected most of the anomalies of the central nervous system and genitourinary system and cases with multiple anomalies, but was less satisfactory in detecting the anomalies of the heart and gastrointestinal tract. The perinatal mortality rate was 4.2 per 1000 in the screening group and 8.4 per 1000 in the control group (p = 0.013). The detection of major fetal anomalies in ultrasound screening can reduce perinatal mortality. A systematic search for fetal anomalies should be included in the ultrasound screening of all pregnancies.

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Section: Discussionmentioning

confidence: 68%

Fetal anomalies in a controlled one-stage ultrasound screening trial. A report from the Helsinki Ultrasound Trial

Saari-Kemppainen¹,

Karjalainen²,

Ylöstalo³

et al. 1994

Jpme

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“…Published values for the incidence of fetal uropathy revealed by routine prenatal ultrasonography from six European centres [ 5, 11, 12, 14 –16] are listed in Table 2. The variation in incidence from 1 in 154 pregnancies reported from Stoke on Trent in the UK, to 1 in 1200 in Lund, Sweden, almost certainly reflects differences in methodology and interpretation rather than genuine differences in the incidence of urinary tract anomalies in the two populations studied.…”

Section: The Incidence Of Fetal Uropathy Detected By Routine Prenatalmentioning

confidence: 99%

Prenatally detected uropathy: epidemiological considerations

Thomas

1998

British Journal of Urology

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“…17 Screening for congenital anomalies in a large series was realized from the late 1970s by Campbell and Pearce 15 and then in Sweden and the United States. 18‐20 Systematic routine ultrasound for identification of congenital anomalies were performed in strictly low‐risk pregnancies during 1984 to 1985, 21 and then in larger populations. 22‐35…”

Section: Brief Historical Comment: From Primary Scans To Fetal Screeningmentioning

confidence: 99%

Routine Ultrasound Screening of Congenital Anomalies: An Overview of the European Experience

Levi

1998

Annals of the New York Academy of Sciences

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Results from ultrasound in low-risk pregnant women are significant when routine screening is performed on a large population because the anomalies are rare. Professionals expect from routine ultrasound objective information that cannot usually be obtained by clinical procedures. Parents seek reassurance about the absence of fetal congenital anomalies and overall fetal health. Therefore, Europeans view routine ultrasound as a part of obstetrical care, capable of filling important gaps by delivering much key information for improving obstetrical practice. Fetal anomalies screening (FAS) requires higher education and qualifications than obstetrical ultrasound. The health insurance systems support ultrasound screening and allow its spread in most European countries; approximately 98% of pregnant women are examined by ultrasound and, frequently, two to three times (usually once per trimester). Detection rate of congenital anomalies is about 28% in geographical areas (private practice and hospitals), 60 to 80% in Ob/Gyn's ultrasound labs. Routine ultrasound screening policy has not proved to result in an immoderate use of ultrasound; on the contrary, chaotic use of routine ultrasound can lead to an unproductive and excessive number of scans. New trends in FAS, such as the early detection of fetal defects and chromosomal anomalies, bring more arguments for routine screening. Effectiveness should increase by enhancing education and training and the systematic referral for FAS to accredited laboratories.

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The advantage of antenatal diagnosis of intestinal and urinary tract malformations

Cited by 24 publications

References 10 publications

Fetal anomalies in a controlled one-stage ultrasound screening trial. A report from the Helsinki Ultrasound Trial

Fetal anomalies in a controlled one-stage ultrasound screening trial. A report from the Helsinki Ultrasound Trial

Prenatally detected uropathy: epidemiological considerations

Routine Ultrasound Screening of Congenital Anomalies: An Overview of the European Experience

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