1943
DOI: 10.1002/ar.1090870106
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The age factor in the response of bone tissue to alizarin dyes and the mechanism of dye fixation

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Cited by 14 publications
(6 citation statements)
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“…The dye disappears when the stained bone is treated with weak acid [Ercoli and Levis, 1943]. This would seem to support the view that ARS is either bonded to the inorganic salts or some ions in the salts.…”
Section: Introductionsupporting
confidence: 70%
See 1 more Smart Citation
“…The dye disappears when the stained bone is treated with weak acid [Ercoli and Levis, 1943]. This would seem to support the view that ARS is either bonded to the inorganic salts or some ions in the salts.…”
Section: Introductionsupporting
confidence: 70%
“…Applied in vivo, and in suitable doses, ARS stains mineralizing bone red. The dye stains bone surfaces [ Brash, 1924;Massler and Schour, 1951;Hoyle, 1956Hoyle, ,1960 and also the surfaces of new endosteal bone [Harris et al, 1964;Hoyle, 1968], whereas large doses are required to stain mature bone [Ercoli and Levis, 1943;Jarabak and Vehe, 1953], ARS has also been used in vitro to demonstrate bone mineralization in fetal bone [Spalleholz, 1914;Noback and Noback, 1944]. Staining of more mature bone has also been shown [ Atherton et al.…”
Section: Introductionmentioning
confidence: 99%
“…Les doses utilise*es (en moyenne 150 mg/kg) sont plus elevoes que celles qui sont preconisees par les auteurs pour des especes differentes : rats, lapins, cochon d'Inde, pores, chiens (Schour, 1936 ;Ercoli et Lewis, 1943;Hoyte, 1968 ;Harris, Travis, Friberg et Radin, 1964). Aux doses inferieures ä 100 mg/kg, les cranes de souris sont insuflisainment colores pour permettre une bonne etude des surfaces endo et exocräniennes.…”
Section: Discussionunclassified
“…The author attributed the teratogenic activity of these compounds to the mutual possession of a diazotized o-tolidine grouping. The influence of age on the response of bone tissue to alizarin dyes was studied by Ercoli and Lewis (118) in mice. Single i.v.…”
Section: Modification Of Drug Activitymentioning
confidence: 99%