The ageing of lung function: cross-sectional and longitudinal studies of an Inuit community

Rode, Andris; Shephard, Roy J.

doi:10.1183/09031936.94.07091653

Cited by 14 publications

(8 citation statements)

References 21 publications

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“…For some symptoms such as shortness of breath, no line of investigation may be selected as the physician, and indeed the patient, may consider its presence to be a natural part of ageing. While it is clear that, starting in the third decade, lung function declines with age, it is also clear that the lung retains sufficient capacity in older persons without lung disease to allow them to function quite well [53][54][55]. The likelihood of clinical inaction with this particular symptom is illustrated in a US study involving almost 21 000 adults.…”

Section: The Second Hurdle -Physician Recognition Of Symptomsmentioning

confidence: 99%

Asthma and ageing: an end user's perspective ‐ the perception and problems with the management of asthma in the elderly

Jones

Iverson

Burns

et al. 2011

Clin Experimental Allergy

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Asthma and ageing: an end user' s perspective-the perception and problems with the management of asthma in the elderly AbstractDespite the high prevalence of asthma in the elderly, its development, diagnosis, and treatment are underresearched. This paper provides a comprehensive review of the current state of knowledge in relation to management of asthma in the elderly -focusing on barriers to diagnosis and treatment and the central role of self-management. Asthma prevalence increases with age, as does the risk of dying from asthma, and with the ageing of the population and increasing life expectancy, the prevalence of (diagnosed and undiagnosed) asthma in older adults is expected to increase drastically, placing an increasing burden on sufferers, the community and health budgets. Asthma sufferers are more likely to be psychologically distressed and at a higher risk of anxiety and depression, more likely to experience a sense of lack of control over their health and to have lower self-reported quality of life. Asthma is under-diagnosed, and under-treated, in the elderly, further exacerbating these negative consequences. The review concludes, among other things, that there is a need to better understand the development and impact of asthma in the elderly, to increase community awareness of asthma in the elderly, to improve both 'medical management' and 'self-management' in this population and to develop more effective tools for diagnosis and treatment of asthma in the elderly. The paper concludes with key recommendations for future research and practice in this area.

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Section: The Second Hurdle -Physician Recognition Of Symptomsmentioning

confidence: 99%

Asthma and ageing: an end user's perspective ‐ the perception and problems with the management of asthma in the elderly

Jones

Iverson

Burns

et al. 2011

Clin Experimental Allergy

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“…Age‐related decreases in physical function, cognitive performance and mental well‐being can limit performance of multiple activities connected with daily living, thus resulting in poor quality of life in the elderly. A large number of cross‐sectional and longitudinal studies carried out mainly in Western populations have shown the age‐related changes in multiple health domains with a general conclusion that with advancing age, physical and cognitive functions decline while depression increases 1–7 . Besides age, the effects of gender on health variables have also been reported 8 with a paradoxical, but one of the most consistent, finding that although females live longer than males, they also tend to report poorer self‐rated health, experience worse health status and have higher disability levels than males of the same age 9,10 …”

Section: Introductionmentioning

confidence: 99%

“…A large number of cross-sectional and longitudinal studies carried out mainly in Western populations have shown Accepted for publication 21 the age-related changes in multiple health domains with a general conclusion that with advancing age, physical and cognitive functions decline while depression increases. [1][2][3][4][5][6][7] Besides age, the effects of gender on health variables have also been reported 8 with a paradoxical, but one of the most consistent, finding that although females live longer than males, they also tend to report poorer self-rated health, experience worse health status and have higher disability levels than males of the same age. 9,10 Although age-related decline in general health is a universal phenomenon, a more interesting question would be how the patterns of change vary across populations living under different conditions; for example, geographical, cultural and socioeconomic environments as many functional domains can be associated with environmental factors.…”

Section: Introductionmentioning

confidence: 99%

Gender‐specific patterns in age‐related decline in general health among Danish and Chinese: A cross‐national comparative study

Wu¹,

Zhang²,

Pang³

et al. 2011

Geriatrics Gerontology Int

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“…Our finding that smoking habits do not exert any influence on BHR is only apparently in contrast to previously reported epidemiologic evidence, and can be explained by the young age of the population studied. In fact, an increase in the risk of BHR has been reported in older subjects (5,10,11).…”

Section: Discussionmentioning

confidence: 97%

Determinants of bronchial responsiveness in the European Community Respiratory Health Survey in Italy: evidence of an independent role of atopy, total serum IgE levels, and asthma symptoms

1998

Allergy

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The aim of the analysis was to test whether total serum IgE levels, specific serum IgE levels, and asthma symptoms are independent predictors of bronchial hyperresponsiveness (BHR), after controlling for known risk factors or potential confounders. The study was carried out on a sample of 875 young adults, 20–44 years old, who took part in the European Community Respiratory Health Survey in Italy The subjects underwent a dose‐response methacholine challenge test. We also measured airway caliber as the baseline FEV, in absolute terms and as percentage of forced vital capacity (FVC); skin wheal response to 11 common environmental allergens; and total and specific serum IgE levels to mites, molds, pets, and respiratory symptoms by means of a standardized questionnaire. Atopy (positive skin prick test and/or positive specific IgE assay), total IgE, asthma symptoms, airway caliher, and age appeared to be independent predictors of BHR. When all the other risk factors were taken into account, atopy and total IgE were associated with a threefold increase in BHR risk and thus emerged as the main determinants of BHR. The importance of symptom status as a determinant of BHR decreased remarkably after controlling for atopy and IgE: the odds ratio of current asthmatics to asymptomatic subjects decreased from 15.3 to 8.8. When controlling for symptoms and atopy, a family history of allergic diseases and early respiratory infections was not found to be associated with BHR. Both FEVi and FEV/FVC were strongly and inversely associated with BHR. When airway caliher was taken into account, older age was associated with decreased responsiveness, and the level of responsiveness did not differ significantly between males and females and between smokers and nonsmokers. The results from this analysis indicate that at any given age, irrespective of sex and smoking habits, total serum IgE, specific IgE, airway caliber, and asthma symptoms are the main independent factors influencing the occurrence of BHR in a young adult sample.

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The ageing of lung function: cross-sectional and longitudinal studies of an Inuit community

Cited by 14 publications

References 21 publications

Asthma and ageing: an end user's perspective ‐ the perception and problems with the management of asthma in the elderly

Asthma and ageing: an end user's perspective ‐ the perception and problems with the management of asthma in the elderly

Gender‐specific patterns in age‐related decline in general health among Danish and Chinese: A cross‐national comparative study

Determinants of bronchial responsiveness in the European Community Respiratory Health Survey in Italy: evidence of an independent role of atopy, total serum IgE levels, and asthma symptoms

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