The Airwave Health Monitoring Study of police officers and staff in Great Britain: Rationale, design and methods

Elliott, Paul; Vergnaud, Anne-Claire; Singh, Deepa; Neasham, David; Spear, Jeanette; Heard, Andy

doi:10.1016/j.envres.2014.07.025

Cited by 95 publications

(140 citation statements)

References 7 publications

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“…We did lookups of our sentinel SNPs in 1 H NMR lipidomics data on plasma (N=2,022) and data from the Metabolon platform (N=1,941) in the Airwave Study30, and used PhenoScanner to test SNPs against published significant ( P < 5 × 10 -8 ) genome vs metabolome-wide associations in plasma and urine (Online Methods). Ten BP SNPs show association with lipid particle metabolites and a further 31 SNPs (8 also on PhenoScanner) show association with metabolites on the Metabolon platform, highlighting lipid pathways, amino acids (glycine, serine, glutamine), tri-carboxylic acid cycle intermediates (succinylcarnitine) and drug metabolites (Supplementary Tables 14 and 15).…”

Section: Resultsmentioning

confidence: 99%

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Εvangelou¹,

Warren²,

et al. 2018

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High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic, pulse pressure) to date in over one million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also reveal shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

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Section: Resultsmentioning

confidence: 99%

“…All analyses were restricted to the 392,092 unrelated individuals of European ancestry from UKB. As a sensitivity analysis to assess for evidence of bias in the UKB results, we also carried out similar analyses in Airwave, an independent cohort of N=14,004 unrelated participants of European descent30 (Supplementary Methods). …”

Section: Methodsmentioning

confidence: 99%

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Εvangelou¹,

Warren²,

et al. 2018

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“…The Airwave Health Monitoring Study is a longitudinal study of British police force employees launched in 2004, with 42,112 participants enrolled at the end of 2012 [15]. Since April 2007, a sub-sample of participants completed a 7-day estimated weighted food diary ( n = 15,404).…”

Section: Introductionmentioning

confidence: 99%

A cross-sectional investigation into the occupational and socio-demographic characteristics of British police force employees reporting a dietary pattern associated with cardiometabolic risk: findings from the Airwave Health Monitoring Study

et al. 2017

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PurposeThe aims of this study were to (1) determine the association between diet quality using the Dietary Approaches to Stop Hypertension (DASH) score and cardiometabolic risk in a British working population and (2) identify employee characteristics associated with reporting a poorer quality dietary pattern.MethodsBritish police employees enrolled (2007–2012) into the Airwave Health Monitoring Study (n = 5527) were included for sex-specific cross-sectional analyses. Dietary intakes were measured using 7-day food records. DASH score was calculated to determine diet quality. Logistic regression evaluated associations between (1) diet quality and increased cardiometabolic risk (defined as ≥ 3 risk markers: dyslipidaemia, elevated blood pressure, waist circumference, CRP or HbA1c), and (2) poor diet quality (lowest fifth of DASH score distribution) and employee characteristics.ResultsEmployees recording a poor diet quality had greater odds (OR) of increased cardiometabolic risk independent of established risk factors (demographic, lifestyle and occupational) and BMI: men OR 1.50 (95% CI 1.12–2.00), women: OR 1.84 (95% CI 1.19–2.97) compared to the healthiest diet group. Characteristics associated with reporting a poor quality diet were employment in Scotland vs. England: men OR 1.88 (95% CI 1.53–2.32), women: OR 1.49 (95% CI 1.11–2.00), longer working hours (≥ 49 vs. ≤40 h) men: OR 1.53 (95% CI 1.21–1.92) women: OR 1.53 (95% CI 1.12–2.09). For men, job strain (high vs. low) was associated with reporting a poor diet quality OR 1.66 (95% CI 1.30–2.12).ConclusionsThe general population disparities in diet quality between England and Scotland were reflected in British police employees. The association of longer working hours and job strain with diet quality supports the targeting of workplace nutritional interventions.Electronic supplementary materialThe online version of this article (doi:10.1007/s00394-017-1562-4) contains supplementary material, which is available to authorized users.

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“…To date there is limited research investigating dietary behaviours and chronic metabolic disease risk in UK shift workers. The aim of this explorative study is to investigate the relationship between shift work and diet using data from the Airwave cohort, a longitudinal health monitoring study of British police force employees (4) . Men (n 853) and women (n 376), mean age 38·4years (SD 8·6years), enrolled into the study between 2004 and 2012, who had work pattern and dietary information available were included for cross-sectional analyses.…”

Section: Department Of Epidemiology and Biostatistics School Of Publmentioning

confidence: 99%

Sex differences in the relationship between work patterns and diet in British police force employees: a nested cross-sectional study

Gibson

Eriksen

Chan³

et al. 2016

Proc. Nutr. Soc.

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The Airwave Health Monitoring Study of police officers and staff in Great Britain: Rationale, design and methods

Cited by 95 publications

References 7 publications

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

A cross-sectional investigation into the occupational and socio-demographic characteristics of British police force employees reporting a dietary pattern associated with cardiometabolic risk: findings from the Airwave Health Monitoring Study

Sex differences in the relationship between work patterns and diet in British police force employees: a nested cross-sectional study

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