2020
DOI: 10.1007/s12011-020-02039-5
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The Antagonistic Effects of Selenium Yeast (SeY) on Cadmium-Induced Inflammatory Factors and the Heat Shock Protein Expression Levels in Chicken Livers

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Cited by 18 publications
(7 citation statements)
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“…Also, the results indicated that Se can effectively interfere with the activation of HSPs induced by HgCl 2 . These findings are compatible with the result that Se can significantly inhibit the activation of HSPs induced by heavy metals in the liver ( Wang et al., 2020a ) and neutrophils ( Xing et al., 2018 ) of chickens.…”
Section: Discussionsupporting
confidence: 91%
“…Also, the results indicated that Se can effectively interfere with the activation of HSPs induced by HgCl 2 . These findings are compatible with the result that Se can significantly inhibit the activation of HSPs induced by heavy metals in the liver ( Wang et al., 2020a ) and neutrophils ( Xing et al., 2018 ) of chickens.…”
Section: Discussionsupporting
confidence: 91%
“…As a result of CdCl 2 (10 mg/kg feed) administration to chickens for 90 days, levels of NF-κB and phosphorylated c-Jun N-terminal kinase (p-JNK)/JNK in the spleen increased significantly, while those of mechanistic target of rapamycin (mTOR) and HSP70 decreased [232]. Exposure of 120 day old layers to Cd (150 mg/kg for 120 days) was associated with oxidative stress, increased NO production, iNOS activity, and increased expression of inflammatory factors (iNOS, NF-κB, TNF-α, and PTGE) and heat-shock proteins (HSPs 27, 40, 60, 70, and 90) in the liver tissues of birds [233]. In livers of duck exposed to a combination of molybdenum and cadmium, mRNA expression of Hsp60, Hsp70, Hsp90, TNF-α, NF-κB, and cyclooxygenase-2 (COX-2) was significantly upregulated [234].…”
Section: And Nf-κbmentioning
confidence: 99%
“…Interestingly, Se (2 mg/kg as sodium selenite for 90 days) was reported to alleviate Cd-induced inflammation and meat quality deterioration via antioxidant and anti-inflammation action [343]. Supplementation with Se-yeast (0.5 mg/kg) was shown to have an antagonistic effect on Cd-induced inflammatory injury in chicken livers [233].…”
Section: Se and CD Toxicitymentioning
confidence: 99%
“…Furthermore, SeY exerted a remarkable anti-inflammatory effect induced by lead by downregulating the gene transcription levels of inflammatory mediators in skeletal muscles such as interleukin (IL)-1β, IL-4, and IL-10 of exposed chicken (Liu et al, 2019). Similarly, dietary supplementation of chicken by 0.5 mg/kg SeY lessened markedly the expression levels of gene and protein related to hepatic inflammatory markers like iNOS, NF-κB, TNF-α, and prostaglandins (Wang et al, 2020b).…”
Section: Introductionmentioning
confidence: 99%