2021
DOI: 10.1016/j.ijbiomac.2021.04.070
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The anti-obesity effects exerted by different fractions of Artemisia sphaerocephala Krasch polysaccharide in diet-induced obese mice

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Cited by 21 publications
(10 citation statements)
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“…49,50 The increased abundance of Actinobacteria in group O3.0 was attributed to dramatic increases of two bacterial families, namely Bifidobacteriaceae and Coriobacteriaceae represented exclusively by the genera Bifidobacterium and Olsenella , respectively, in the gut microbiota of the obese rats. While many probiotic Bifidobacterium strains are well-documented to attenuate hepatic steatosis and inflammation in rodent models of fatty liver disease, 51,52 an increased abundance of Coriobacteriaceae and its genus Olsenella in obese mice was found to be associated with antiobesity effects of Artemisia polysaccharides 53 and has been hypothesized to be responsible for hepatoprotective and antisteatotic effects of camellia oil in diet-induced obese mice. 50 A further striking change in the gut microbiota of group O3.0 was a strong increase in the abundance of Lactobacillaceae (Firmicutes phylum), which were represented only by the genus Lactobacillus .…”
Section: Discussionmentioning
confidence: 99%
“…49,50 The increased abundance of Actinobacteria in group O3.0 was attributed to dramatic increases of two bacterial families, namely Bifidobacteriaceae and Coriobacteriaceae represented exclusively by the genera Bifidobacterium and Olsenella , respectively, in the gut microbiota of the obese rats. While many probiotic Bifidobacterium strains are well-documented to attenuate hepatic steatosis and inflammation in rodent models of fatty liver disease, 51,52 an increased abundance of Coriobacteriaceae and its genus Olsenella in obese mice was found to be associated with antiobesity effects of Artemisia polysaccharides 53 and has been hypothesized to be responsible for hepatoprotective and antisteatotic effects of camellia oil in diet-induced obese mice. 50 A further striking change in the gut microbiota of group O3.0 was a strong increase in the abundance of Lactobacillaceae (Firmicutes phylum), which were represented only by the genus Lactobacillus .…”
Section: Discussionmentioning
confidence: 99%
“…Our results corroborate these findings. 20 In conclusion, MET-SSPS-NPs significantly inhibit the HFD-induced increase of serum lipids.…”
Section: Resultsmentioning
confidence: 83%
“…These ASKPcaused changes in the microbial composition of mice is proved to be beneficial in improving obesity related metabolic disorders. 17,18,45 This suggests that the intake of ASKP has potential health benefits by improving the dysbiosis induced by a high-fat diet. Recent studies have shown that the gut microbiota can interact with the host by producing metabolites, which are small molecules representing intermediates or end-products of microbial metabolism.…”
Section: Discussionmentioning
confidence: 99%