“…Nanotechnology-based approaches, predominantly different types of NPs, metal organic frameworks (MOFs), and other nanomaterials, are also amongst the most studied line of attack to deal with pathogenic biofilms [ 22 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 35 , 36 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ]. Natural plant-based products are being developed to help overcome the problem with multidrug-resistant bacteria, namely plant extracts and isolated compounds, as well as essential oils that contain large amounts of phytochemicals [ 33 , 34 , 37 , 38 , 39 , 40 , 41 , 42 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ]. In addition, physical approaches (cryogenic freezing, ultrasound), bacteriophages, electrochemical treatments, photodynamic therapy (PDT), combination approaches, and other strategies are also among a few other examples that are being presently implemented [ 26 , 30 , ...…”