The Antioxidant Activity and Phytochemical Analysis of Medicinal Plant Veronica Biloba

Hassan, Abul; Ullah, Himayat; Israr, Muhammad

doi:10.25026/jtpc.v5i1.225

Cited by 5 publications

(8 citation statements)

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“…e Soxhlet hot continuous method of extraction was followed according to reports [11,12,17,18] for both plants. At first, two sterilized porous bags were manually prepared, in which each possesses 20 gm by weight of the fully powdered plant.…”

Section: Soxhlet Extractionmentioning

confidence: 99%

“…is genus has a unique chemotaxonomic and phytochemical importance and is widely utilized in Turkish and Traditional Chinese Herbal Medicine (TCM) for treating tonics, influenza, diuretics, expectorants, restoratives, and respiratory diseases [10]. Previously, we have determined a strong antibacterial and antifungal potential of Veronica biloba extracts [11] as well as phytochemicals and antioxidants comparable with standard acarbose potential [12]. e family Cyperaceae mostly possesses fibrous halophytic plants; one genus of this family is Schoenoplectus present in the river territories of Pakistan, India, Africa, Morocco, and Spain at the extreme Mediterranean [13,14]; about 49 compounds are extracted from the specie of Schoenoplectus lacustris and evaluated for eutrophic spots; a bioindicator was tested on algae green Selenastrum capricornutum and showed positive potential in comparison with copper sulphate, algaecide [15].…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant, Antidiabetic, and Antihypertension Inhibitory Potentials of Phenolic Rich Medicinal Plants

Hassan

Mohmand²,

Ullah³

et al. 2022

Journal of Chemistry

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Veronica (Plantaginaceae) and Schoenoplectus have a unique chemotaxonomic and phytochemical importance and are widely utilized in Turkish and Traditional Chinese Herbal Medicine (TCM) for treating tonics, influenza, diuretics, expectorants, restoratives, and respiratory diseases, and both are very useful in treating infectious and metabolic disorders as well. This study evaluates two medicinal plant species, Veronica biloba and Schoenoplectus triqueter (L.) Palla; extraction was performed through Soxhlet and maceration methods as well as determination of free and bound phenolics. Evaluated biological screening of (extracts and phenolics) angiotensin-I converting enzyme (ACE), Type-II diabetes (α-glucosidase and α-amylase), and antioxidants potential was performed using modified assays. The angiotensin-I converting enzyme (ACE) 50% inhibition potential in Veronica biloba was found at IC50 = 210.68 μg/mL and in Schoenoplectus triqueter (L.) Palla at IC50 = 229.40 µg/mL, respectively. Meanwhile Type-II diabetes with α-amylase 50% inhibition shown by bound phenolics of Veronica biloba at IC50 = 219.66 µg/mL and its water extract at IC50 = 110.09 µg/mL possesses higher potential, and α-glucosidase potential by free phenolics was found to be active at IC50 = 469.56 µg/mL, while water and ethyl acetate extracts showed higher potential, IC50 = 78.65 µg/mL and IC50 = 97.03 µg/mL, than the standard acarbose, recorded lower. In case of amylase, α-glucosidase showed IC50 = 88.73 μg/mL. Our results showed that both plants possess a direct relationship with the increase in the concentration of extracts and inhibited very strongly angiotensin-I converting enzyme (ACE) and Type-II diabetes (α-glucosidase and α-amylase). The properties of enzyme hindrance may be associated with phenolic compounds and rich phenolic plant antioxidant potential provides a route to the elucidation of natural antihypertension and antidiabetes.

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Section: Soxhlet Extractionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antioxidant, Antidiabetic, and Antihypertension Inhibitory Potentials of Phenolic Rich Medicinal Plants

Hassan

Mohmand²,

Ullah³

et al. 2022

Journal of Chemistry

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“…Further, the increase in different phenolics and flavonoids can help to mitigate the radiation stress-induced damage. Each phytochemical has a distinct biological action, that may lead to the development of new composites as anti-microbials combat pathogens or to help improve human health (Hassan et al, 2019).…”

Section: Phytochemical Screening Of the Ethanolic Extractmentioning

confidence: 99%

Physiological variation of irradiated red radish plants and their phylogenic relationship using SCoT and CDDP markers

Aly

Eliwa

Borik

et al. 2021

Not Bot Horti Agrobo

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Greenhouse experiment is carried out to explore the outcome of γ-radiation on physiological and genetic variation in red radish (Raphanus sativus) for two generations. Gamma rays from 60Co were used to penetrate red radish seeds with different dose levels (0.0, 10, 20, 40 and 80 Gy). Plants generated from irradiated seeds and from self-pollination of these plants, called M1 and M2 generations, respectively. Some morphological and physiological traits were then determined, and the genetic diversity of both generations was studied using Start Codon Targeted (SCoT) and Conserved DNA-Derived Polymorphism (CDDP) molecular markers. All studied morphological traits (number of leaves/plants, leave height, root diameter, and root weight) were steadily improved by raising irradiation dose rate, reaching a cumulative raise at the irradiation doe level 40 Gy and decreased at dose level 80 Gy. Photosynthetic pigments of red radish plants released a notable increase by increasing gamma rays dose level for chlorophyll (a), chlorophyll (b) and carotenoids for 40 Gy dose rate. Proline content was elevated proportionally to the irradiation dose level, with the greatest increase seen at dose level of 80 Gy. Moreover, phytochemical screening was detected for the both two generations. Fourteen SCoT primers generated a total number of banding patterns of 194 with average 13.86 and the primer SCoT-33 released the highest number banding patterns (21). The percentage mean of polymorphism for all the SCoT primers was 74.66% and was 66.49 and 63.74% for M1 and M2 respectively. Furthermore, fifteen CDDP primers generated a total number of banding patterns of 186 and the primer CDDP-5 relieved the highest number of banding patterns (20). The percentage mean of polymorphism for all the CDDP primers was 73.41% and was 64.38 and 65.91% for M1 and M2 respectively. It could be concluded that gamma irradiation exhibited an appropriate variation in red radish M1 and M2 which was detected by SCoT and CDDP molecular markers.

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“…e antioxidant activity was performed according to the previously reported one in [25][26][27][28] using a stable DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging power assay for all the entire fraction extracts such as n-hexane, water, dichloromethane, and ethyl acetate. All the extracts were first dissolved in suitable solvent dimethylsulfoxide (DMSO) at various concentrations of 31.25, 62.5, 125, 250, and 500 µg/mL by dilution method.…”

Section: Antioxidant Activitymentioning

confidence: 99%

The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla

Hassan

Akmal

Khan

2020

Journal of Chemistry

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Over the centuries, humans use different types of therapeutic plants to treat several diseases. Cyperaceae family has a significant number of monocotyledon plants, and Schoenoplectus is one of the genera that belong to this family; about forty-nine compounds are isolated. Our current study was evaluated on Schoenoplectus triqueter L. Palla to show the potential of its antioxidants and confirm the phytochemical constituents in this plant species. Fully powdered plant taken for successive extraction process in hot continuous process for Soxhlet was 20 g plant in porous bag manually prepared; the constant temperature provided was 40–50°C. In the maceration extraction method, 30 g plant was taken in a closed jar and the solvent placed for extraction was 300 mL of ethanol; the extract gets filtered and fractioned to different solvents such as water, dichloromethane, ethyl acetate, and n-hexane fraction. Important types of phytochemicals found in this species are alkaloids, proteins, amino acids, flavonoids, phenols, terpenoids, tannins, saponins, and carbohydrates. All the entire extracted fractions which are water, dichloromethane, ethyl acetate, and n-hexane possess noticeable activity at various concentrations of 31.25, 62.5, 125, 250, and 500 µg/mL by the dilution method. The ethyl acetate extract holds greater median inhibitory concentration (IC50 = 3.52 ± 0.01), and water showed IC50 = 3.61 ± 0.01 percent potential as compared to the standard ascorbic acid which possesses IC50 = 2.27 ± 0.01. Their potential may be enhanced or lowered with the purification of extracts which might be useful in biological activities.

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The Antioxidant Activity and Phytochemical Analysis of Medicinal Plant Veronica Biloba

Cited by 5 publications

References 0 publications

Antioxidant, Antidiabetic, and Antihypertension Inhibitory Potentials of Phenolic Rich Medicinal Plants

Antioxidant, Antidiabetic, and Antihypertension Inhibitory Potentials of Phenolic Rich Medicinal Plants

Physiological variation of irradiated red radish plants and their phylogenic relationship using SCoT and CDDP markers

The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla

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