The antioxidant potential of different edible and medicinal mushrooms

Mwangi, R. W.; Macharia, John M.; Wagara, I. N.; Raposa, László Bence

doi:10.1016/j.biopha.2022.112621

Cited by 105 publications

(89 citation statements)

References 111 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Over the last century, many studies have shown that there is an inverse relationship between antioxidant intake and various health problems, such as cancer, cardiovascular disease, and diabetes [ 50 , 51 , 52 , 53 ]. Antioxidants can be described as powerful shields against the negative effects of free radicals.…”

Section: Resultsmentioning

confidence: 99%

Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy Shelves

et al. 2022

View full text Add to dashboard Cite

Spathodea campanulata is an important medicinal plant with traditional uses in the tropical zone. In the current work, we aimed to determine the chemical profiles and biological effects of extracts (methanolic and infusion (water)) from the leaves and stem bark of S. campanulata. The chemical components of the tested extracts were identified using LC-ESI-QTOF-MS. Biological effects were tested in terms of antioxidant (radical scavenging, reducing power, and metal chelating), enzyme inhibitory (cholinesterase, amylase, glucosidase, and tyrosinase), antineoplastic, and antiviral activities. Fifty-seven components were identified in the tested extracts, including iridoids, flavonoids, and phenolic acids as the main constituents. In general, the leaves-MeOH extract was the most active in the antioxidant assays (DPPH, ABTS, CUPRAC, FRAP, metal chelating, and phosphomolybdenum). Antineoplastic effects were tested in normal (VERO cell line) and cancer cell lines (FaDu, HeLa, and RKO). The leaf infusion, as well as the extracts obtained from stem bark, showed antineoplastic activity (CC50 119.03–222.07 µg/mL). Antiviral effects were tested against HHV-1 and CVB3, and the leaf methanolic extract (500 µg/mL) exerted antiviral activity towards HHV-1, inhibiting the viral-induced cytopathic effect and reducing the viral infectious titre by 5.11 log and viral load by 1.45 log. In addition, molecular docking was performed to understand the interactions between selected chemical components and viral targets (HSV-1 DNA polymerase, HSV-1 protease, and HSV-1 thymidine kinase). The results presented suggest that S. campanulata may be a bright spot in moving from natural sources to industrial applications, including novel drugs, cosmeceuticals, and nutraceuticals.

show abstract

Section: Resultsmentioning

confidence: 99%

Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy Shelves

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The total antioxidant capacity, hydroxyl radical, and superoxide anion radicals were measured with the corresponding kits of Nanjing Jiancheng Biotechnology Co., Ltd. Nanjing, China. The free radical scavenging ability was determined by the DPPH method ( Mwangi et al, 2022 ). A total of 1, 2, 3, 4, and 5 mg/ml crude polysaccharides were used to determine the antioxidant activities in vitro .…”

Section: Methodsmentioning

confidence: 99%

Effects of Different Bud Thinning Methods on Nutritional Quality and Antioxidant Activities of Fruiting Bodies of Pleurotus eryngii

Liu

Wang²,

Li³

et al. 2022

Front. Plant Sci.

View full text Add to dashboard Cite

The cultivation of Pleurotus eryngii was studied by different methods, such as puncturing and fixed-point mushroom production, shading treatment at the top of the bag, and pulling the top of the bag. The agronomic characters, yield, nutritional components, and antioxidant activities in vitro of fruiting bodies of P. eryngii were determined. The results showed that the number of buds in the perforated treatment was less than that in the production method of traditional fruiting bodies to a certain extent. When a circular hole with a diameter of 1.5 cm was drilled in the perforated treatment, the number of buds was 5, which was less than that in the control group. The efficiency of artificial removal of buds was significantly higher than that of the control group, but the harvesting date was longer than that of other methods. The number of buds in shading treatment and bag opening treatment was significantly less than that in the control group, which could effectively control the number of buds and reduce the cost of manpower and material resources. In terms of nutritional components, the A3 treatment group with a hole diameter of 1.0 cm and a quantity of one had the highest crude protein content of 151.34 g, and a significant difference was observed in crude fiber content compared with other treatments. The extraction rate of B5 crude polysaccharide was the highest, and the extraction rate was 12.90%. The antioxidant activities in vitro increased with the increase of crude polysaccharide concentration. Using A3 treatment to cultivate fruiting bodies is conducive to meeting people’s requirements for improving quality of life.

show abstract

“…It has been proved that flavonoids pharmacological effects are correlating with their antioxidant potentialities [22]. Carotenoids and ascorbic acid are also important functional plant components [23][24][25][26]. Carotenoids, vegetable dyes present in the chloroplasts and chromophores, play an auxiliary role in the process of photosynthesis [23].…”

Section: Contents Of Total Flavonoid Total Carotenoid and L-ascorbic ...mentioning

confidence: 99%

“…Vegetable carote-noids have antioxidant activity and can prevent vitamin A deficiencies [24]. Ascorbic acid is an antioxidant vitamin that acts synergistically with tocopherol to preserve antioxidant function in chronic disease states [25]. Ascorbic acid also has a protective function against photo oxidation processes [26].…”

Section: Contents Of Total Flavonoid Total Carotenoid and L-ascorbic ...mentioning

confidence: 99%

Phytochemicals, Antioxidant and Anticancer Properties of Camellia japonica L. Mistletoe Extracts

Kin

Kim²

2022

J.Trop.Life.Science

View full text Add to dashboard Cite

The present study aims to investigate the phytochemical profiles, in vitro antioxidant and antiproliferative properties of methanol and 70% ethanol extracts of Camellia mistletoe. Both extracts were analyzed for contents of total flavonoid, total carotenoid and L-ascorbic acid, and antioxidant properties such as scavenging capacities (1,1-diphenyl-2-picrylhydrazyl, O2- and NO), ferrous ion chelating and reducing power. MTT assay was used to assess the antiproliferative properties against human cancer cell lines. The results showed that the methanol extracts of Camellia mistletoe contained higher total flavonoids (16237 mg rutin equivalents/100 g) and carotenoids (49175 mg/100g) with higher DPPH (IC50 = 0.6 mg/mL), superoxide (IC50 = 0.6 mg/mL), nitric oxide (IC50 = 0.5 mg/mL) radical scavenging and reducing power (IC50 = 1.1 mg/mL) activities than those of ethanol extracts (p < 0.05). In addition, methanol extracts showed much higher antiproliferative activity against A375 (IC50 = 118.1 μg/mL) and HCT116 (IC50 = 148.4 μg/mL) cells than ethanol extracts whereas higher inhibitory effects of MCF7 (IC50 = 139.9 μg/mL), Hela (IC50 = 127.1 μg/mL) and HepG2 (IC50 = 84.2 μg/mL) cell proliferation in the ethanol extracts of Camellia mistletoe. The data from this study suggest that Camellia mistletoe is a potential source of phytochemical compounds with antioxidant and antiproliferative properties.

show abstract

The antioxidant potential of different edible and medicinal mushrooms

Cited by 105 publications

References 111 publications

Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy Shelves

Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy Shelves

Effects of Different Bud Thinning Methods on Nutritional Quality and Antioxidant Activities of Fruiting Bodies of Pleurotus eryngii

Phytochemicals, Antioxidant and Anticancer Properties of Camellia japonica L. Mistletoe Extracts

Contact Info

Product

Resources

About