The antiproliferative and antimicrobial effects of cultivated <i>Anabaena circinalis</i> Rabenhorts ex Bornet and Flahault and <i>Nostoc entophytum</i> Bornet and Flahault

Abstract

diffusion method in order to determine their antimicrobial effects. The anti-cancer activities of these two algae were tested against cancerous cell lines using BrdU cell proliferation ELISA method. The inhibition of these algae ethanol and butanol extracts were tested against Vero and HeLa carcinoma cells in concentrations of 100, 250 and 500 μg/mL. Results: Anabaena circinalis (AC) and Nostoc entophytum (NE) antimicrobial properties against the tes organisms. The buffer extract obtained from AC showed the highest level of antimicrobial activity against L. monocytogenes ATCC 7644 while the buffer extract from NE displayed the highest antimicrobial activity against E. coli O 157:H7. The anti-proliferative data indicate that NE has effective anti-cancer properties. Furthermore, the results showed that cyanobacteria species were superior to DMSO and control groups in terms of anti-cancer activity in tumor cells. NE exhibited significant (p < 0.05) anti-proliferative effects at all three concentrations (100, 250, 500 μg/mL), compared to DMSO while AC exhibited significant anti-proliferative activity only at 500 μg/mL concentration (p < 0.01). Conclusion: The results indicate that extracts possess antimicrobial and antiproliferative antivities. However, further studies are required to ascertain their clinical efficacy.

<p>Biofabrication And Antitumor Activity Of Silver Nanoparticles Utilizing Novel Nostoc sp. Bahar M</p>

“…These compounds possess a variety of biological activities and chemical structures, and include cyclic and linear lipopeptides, fatty acids, alkaloids, and other organic chemicals 28. Many reports have mentioned the antibacterial,29 antifungal,30 and cytotoxic31 properties of these compounds. Extract from blue green algae contains several types of biomolecules that can perform reduction and capping reactions in the reduction and the stabilization processes of synthesizing NPs 24,32.…”

The synergistic effect of dielectric barrier discharge plasma and phycocyanin on shelf life of Oncorhynchus mykiss rainbow fillets

“…statistical analysis is performed using SPSS software, employing One-way analysis of variance with 95% confidence intervals to identify significant differences among the variables. Means are compared using Tukey's test, and The results are presented graphically 31 .…”

Aquatic microalgae “Anabaena oryzae”: phenolic compounds, antioxidant activity and antibacterial activity against Streptococcus mutans oral bacteria

“…It can be concluded that Anabaena extract possesses the potential antibacterial substances that can be used against oral pathogens and for dental caries prevention. metabolites have essential properties (Rashad et al, 2018;Yücer et al, 2018;Rashad and El-Chaghaby, 2020). These aquatic microorganisms represent a vast source of metabolites such as alkaloids, carbohydrates, flavanoids, pigments, phenols, saponins, steroids, tannins, terpenes and vitamins (Rashad et al, 2019).…”