The antisaccade task as a research tool in psychopathology: A critical review

Hutton, Samuel B.; Ettinger, Ulrich

doi:10.1111/j.1469-8986.2006.00403.x

Cited by 460 publications

(452 citation statements)

References 154 publications

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“…Deficits sustaining attention and inhibiting context-inappropriate responses are well established in schizophrenia (38,11). Both types of deficits are promising endophenotypes for the disorder insofar as they are evident at illness onset, persist over the course of the disorder, and are found among unaffected relatives (39,40,41,12).…”

Section: Decreased Attention Fixation and Inhibitory Deficit In Schizmentioning

confidence: 99%

“…Multiple studies have reported elevated antisaccade error rates in schizophrenia patients (10,11,12) which are believed to represent disturbances in the prefrontally-mediated ability to voluntarily suppress prepotent responses (7,13). Patients followed longitudinally show a persistent elevation in antisaccade error rates over time, suggesting an enduring deficit of prefrontal functioning (14,15,16).…”

Section: Introductionmentioning

confidence: 99%

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Reduced Attentional Engagement Contributes to Deficits in Prefrontal Inhibitory Control in Schizophrenia

Reilly

Harris

Khine

et al. 2008

Biological Psychiatry

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BACKGROUND-Problems with the voluntary control of behavior, such as those leading to increased antisaccade errors, are accepted as evidence of prefrontal dysfunction in schizophrenia. We previously reported that speeded prosaccade responses, i.e. shorter response latencies for automatic shifts of attention to visual targets, were associated with higher antisaccade error rates in schizophrenia. This suggests that dysregulation of automatic attentional processes may contribute to disturbances in prefrontally-mediated control of voluntary behavior.

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Section: Decreased Attention Fixation and Inhibitory Deficit In Schizmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Reduced Attentional Engagement Contributes to Deficits in Prefrontal Inhibitory Control in Schizophrenia

Reilly

Harris

Khine

et al. 2008

Biological Psychiatry

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“…A typical antisaccade task requires the participant to move their gaze in the opposite direction to a presented stimulus (Hutton & Ettinger, 2006). In order to do this successfully, participants must inhibit the prepotent oculomotor response of directing their gaze towards a newly presented stimulus.…”

mentioning

confidence: 99%

Attentional modulation of the carry over of eye-movements between tasks

et al. 2016

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Task demands that influence scanning behaviour in one task can cause that behaviour to persist to a second unrelated task (carry over). This can also affect performance on a second task (e.g., hazard perception ratings), and has been attributed to a process of attentional bias that is modulated by top-down influences (Thompson & Crundall, 2011). In a series of experiments we explored how these top-down influences impact upon carry over. In all experiments, participants searched letters that were presented horizontally, vertically, or in a random array. They were then presented with a driving scene and rated the hazardousness of the scene. Carry over of eye-movements from the letter search to the scene was observed in all experiments. Furthermore, it was demonstrated that this carry over effect influenced hazard perception accuracy. The magnitude of carry over was correlated with task switching abilities, attentional conflicting, and attentional orienting (Experiment 1), and was affected by predictability of the primary task (Experiment 2). Furthermore, direct current stimulation of the left dorsolateral prefrontal cortex and parietal areas affected the magnitude of the effect (Experiment 3). These results indicate that carry over is modulated by the specific ability to orient attention and disengage from this orientation. Over orienting leads to increased carry over and insufficient task switching is detrimental to task performance. As a result the current experiments provide evidence that the carry over effect is strongly influenced by attentional processes, namely orienting, inhibition, and task switching.

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“…In the prosaccade paradigm, participants were required to perform simple saccadic eye movements toward a peripheral target when it appeared randomly in the right or left visual field (for a review, see Hutton & Ettinger, 2006). In visual word reading, participants were required to passively see the word stimuli or make orthography judgement tasks (for a review, see McCandliss, Cohen, & Dehaene, 2003).…”

Section: Methodsmentioning

confidence: 99%

A meta‐analysis of functional magnetic resonance imaging studies of eye movements and visual word reading

Zhou

Shu

2017

Brain and Behavior

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IntroductionThe pattern of eye movements during reading is substantially correlated with linguistic factors. While there have been a large number of studies on the neural mechanisms of eye movements and word reading separately, a limited number of studies have compared the activation patterns of these two processes and discussed the associations of their corresponding brain regions within the framework of naturalistic reading.MethodsThis study conducted a meta‐analysis of the existing functional magnetic resonance imaging literature on prosaccades and visual word reading using the activation likelihood estimation algorithm.ResultsOur main finding was that, although prosaccades and word reading mainly activated dorsal and ventral brain areas, respectively, they both activated the left precentral gyrus (PreCG), left superior parietal lobe, right PreCG, right lingual gyrus, and bilateral medial frontal gyrus.ConclusionThese findings provide new insights into cognitive processes involved with naturalistic reading, which requires both eye movements and word reading.

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The antisaccade task as a research tool in psychopathology: A critical review

Cited by 460 publications

References 154 publications

Reduced Attentional Engagement Contributes to Deficits in Prefrontal Inhibitory Control in Schizophrenia

Reduced Attentional Engagement Contributes to Deficits in Prefrontal Inhibitory Control in Schizophrenia

Attentional modulation of the carry over of eye-movements between tasks

A meta‐analysis of functional magnetic resonance imaging studies of eye movements and visual word reading

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