The aptness of antagonistic protocol in intracytoplasmic sperm injection: Embryologic study

Abstract

Introduction Background and objective: Infertility and poor ovarian response are serious problems in our society; fortunately the in vitro fertilization and intracytoplasmic sperm injection technique dissolve many of these problems. This study aimed to assess the effect of an individualized GnRH antagonist regimen on intracytoplasmic sperm injection process especially the aptness of it in given mature reiterative oocytes, normal fertilization, and acceptably zygote cleavage which enhance pregnancy. Methods: The population of the study consisted of 877 couples attending the in vitro fertilization-infertility center in the maternity teaching hospital and chose to undergo intracytoplasmic sperm injection after using of antagonist protocol for stimulation of women ovaries. The women ages ranged between 24 and 44 years. The collected data included a number of reiterative oocytes; fertilization, embryo grades and lastly estimates the pregnancy results Results: A significant association (P <0.001) was found in the numbers of reiterative oocytes between the age groups of the study. A significant association (P = 0.005) was also found concerning to quality of fertilization process. The study of the zygote cleavage and blastomeres formation followed the fertilization show variable grade of embryos and analyzed data of embryo grades in this study indicate presence of significant association (P = 0.003). The rate of pregnancy showed significant association between the groups of the study with the <30 years age group have chance of pregnancy higher than other groups. Conclusion: The antagonist protocol of ovary stimulation according to the results of this study is a qualified protocol; besides it is rapid and can be reversed. This protocol can give effective results in the intracytoplasmic sperm injection process especially for young women, and enhance the pregnancy.

Evaluation The Sero-Prevalence of Cytomegalovirus Infection among Abortion Women in Baqubah city

“…The existence of IgG, which was evident in the prior infection, does not stop reinfection or reactivation but may decrease the degree of pathogenicity. While IgM immunoglobulin, which forms right after infection and vanishes within a brief (16)(17)(18)(19)(20) weeks, was thought to be a sign of recent or acute infection [17] According to the current study, 96.3% of women who had abortions were seropositive for HCMV. Numerous investigations were conducted in Iraq to determine the seropositivity of HCMV in women who had abortions, in a study conducted in Baquba showed the seropositivity of HCMV was 16.8% [18], while in Wasit Province had an HCMV seropositivity of 60.2%, Baghdad had a seropositivity of 10%, and Sulimania County had a seropositivity of 9.18% [19].…”

“…In Erbil city, Ali and Sharef, [20] found that the serupositivity of HCMV was 30.5%. In Babylon AL-Hajjar and Al-Mousawi, [21] southern Iraq, has a high seroprevalence of HCMV IgG antibodies (90%) [22].…”

“…In a previous study, the value of induced abortions in low-income women was poor; the majority had them at health facilities, but 4% had them at home in communities with medical colleges nearby, while no difficulties occurred; there were also misunderstandings and a lack of information [45]. Raza et al [46] found that the age group (15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) years had the greatest rate of women who had abortions in Kirkuk, Iraq.…”