The Arabidopsis endoplasmic reticulum associated degradation pathways are involved in the regulation of heat stress response

Li, Lin-Mao; Lü, Shiyou; Li, Rongjun

doi:10.1016/j.bbrc.2017.04.066

Cited by 33 publications

(26 citation statements)

References 29 publications

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“…The bZIP genes bZIP28 , bZIP2 , bZIP53 , and bZIP60 play positive roles in abiotic stress signaling and responses [ 62 , 63 ], as well as growth and development [ 23 , 64 ]. However, little is known about the roles of BnbZIP13 and BnbZIP41 .…”

Section: Discussionmentioning

confidence: 99%

Genome-Wide Identification and Structural Analysis of bZIP Transcription Factor Genes in Brassica napus

Zhou

Jia

et al. 2017

Genes

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The basic region/leucine zipper motif (bZIP) transcription factor family is one of the largest families of transcriptional regulators in plants. bZIP genes have been systematically characterized in some plants, but not in rapeseed (Brassica napus). In this study, we identified 247 BnbZIP genes in the rapeseed genome, which we classified into 10 subfamilies based on phylogenetic analysis of their deduced protein sequences. The BnbZIP genes were grouped into functional clades with Arabidopsis genes with similar putative functions, indicating functional conservation. Genome mapping analysis revealed that the BnbZIPs are distributed unevenly across all 19 chromosomes, and that some of these genes arose through whole-genome duplication and dispersed duplication events. All expression profiles of 247 bZIP genes were extracted from RNA-sequencing data obtained from 17 different B. napus ZS11 tissues with 42 various developmental stages. These genes exhibited different expression patterns in various tissues, revealing that these genes are differentially regulated. Our results provide a valuable foundation for functional dissection of the different BnbZIP homologs in B. napus and its parental lines and for molecular breeding studies of bZIP genes in B. napus.

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Section: Discussionmentioning

confidence: 99%

Genome-Wide Identification and Structural Analysis of bZIP Transcription Factor Genes in Brassica napus

Zhou

Jia

et al. 2017

Genes

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“…In addition to salt and drought stresses, ERAD defects also cause abnormal responses to other abiotic stresses in plants. The hrd1a/1b double mutant is more tolerant to heat (Li et al , ), and hrd3a and hrd1a/1b exhibit a selenite‐sensitive phenotype (Van Hoewyk, ). Thus, ERAD is essential in various abiotic stress responses.…”

Section: Erad Functions In Abiotic Stressesmentioning

confidence: 99%

Insights into endoplasmic reticulum‐associated degradation in plants

Chen

Xie

2020

New Phytologist

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Summary Secretory and transmembrane protein synthesis and initial modification are essential processes in protein maturation, and these processes are important for maintaining protein homeostasis in the endoplasmic reticulum (ER). ER homeostasis can be disrupted by the accumulation of misfolded proteins, resulting in ER stress, due to specific intra‐ or extracellular stresses. Processes including the unfolded protein response (UPR), ER‐associated degradation (ERAD) and autophagy are thought to play important roles in restoring ER homeostasis. Here, we focus on summarizing and analysing recent advances in our understanding of the role of ERAD in plant physiological processes, especially in plant adaption to biotic and abiotic stresses, and also identify several issues that still need to be resolved in this field.

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“…Indeed, 4 genes with homology to the A. thaliana Hsf2B gene (AT4G11660) were found in the genome of P. patens, among which, two were found up-regulated at 1 h at 37 • C: Pp3c21_18820 (fold change =4.6, p-value=0.00000503) and Pp3c22_9250 (fold change = 3.49, p-value = 0.000274674) suggesting a possible negative regulation exerted by these Hsf2B-homologous genes on the HSR. Alternatively, Li et al [33] suggested that the activation of one of the Endoplasmic Reticulum Associated Degradation (ERAD) pathways (Cytosolic Protein Response (CPR)) by heat stress may lead to the termination of the HSR in an attempt to avoid excessive responses in A. thaliana plants and maintain protein homeostasis through Hsf2B. However, the involvement of Hsf2B-related genes as negative regulators or the ERAD pathways in inhibiting the HSR response need to be experimentally addressed in P. patens.…”

Section: Dynamics Of the Transcriptional Response Of P Patens To Higmentioning

confidence: 99%

Dynamics of the Transcriptome Response to Heat in the Moss, Physcomitrella patens

Elzanati

Mouzeyar

Roche

2020

IJMS

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Thermal stress negatively impacts crop yields, and as the overall temperature of the earth’s atmosphere is gradually increasing, the identification of the temperature transduction pathway of the heat signal is essential in developing new strategies in order to adapt plant breeding to warmer climates. Heat stress damages the molecular structures and physiological processes in plants in proportion to the level and duration of the stress, which leads to different types of responses. In general, plants respond more efficiently when they are first subjected to a moderate temperature increase before being subjected to a higher temperature stress. This adaptive response is called the acclimation period and has been investigated in several plant species. However, there is a lack of information on the dynamic of the Heat Shock Response (HSR) over a continuous period of temperature rise without an acclimation period. In this paper, we investigated the effects of mild (30 °C) and high (37 °C) continuous heat stress over a 24-h period. Through RNA-Seq analysis, we assessed the remodeling of the transcriptome in the moss Physcomitrella patens. Our results showed that the 30 °C treatment particularly affected the expression of a few genes at 1 and 24 h, suggesting a biphasic response. Up-regulated genes at 1 h encode mainly HSR proteins (protein folding and endoplasmic reticulum stress), indicating an early heat response; while the up-regulated genes at 24 h belong to the thiamine biosynthesis pathway. In contrast, the genes involved in photosynthesis and carbon partitioning were repressed by this treatment. Under a higher temperature stress (37 °C), the induction of the HSR occurred rapidly (1 h) and was then attenuated throughout the time points investigated. A network approach (Weighted Gene Correlation Network Analysis, WGCNA) was used to identify the groups of genes expressing similar profiles, highlighting a HsfA1E binding motif within the promoters of some unrelated genes which displayed rapid and transient heat-activation. Therefore, it could be suggested that these genes could be direct targets of activation by a HsfA1E transcription factors.

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The Arabidopsis endoplasmic reticulum associated degradation pathways are involved in the regulation of heat stress response

Cited by 33 publications

References 29 publications

Genome-Wide Identification and Structural Analysis of bZIP Transcription Factor Genes in Brassica napus

Genome-Wide Identification and Structural Analysis of bZIP Transcription Factor Genes in Brassica napus

Insights into endoplasmic reticulum‐associated degradation in plants

Dynamics of the Transcriptome Response to Heat in the Moss, Physcomitrella patens

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