2011
DOI: 10.1136/gut.2010.221168
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The Asia-Pacific Colorectal Screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjects

Abstract: The APCS score based on age, gender, family history and smoking is useful in selecting asymptomatic Asian subjects for priority of colorectal screening.

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Cited by 262 publications
(353 citation statements)
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“…Third, the SP risk score proposed in our study was developed in a reallife cohort, including symptomatic and asymptomatic patients, and hence generalizability to a screening population needs to be further examined. Fourth, the ability of identifying patients with 1 LPD SP, using the clinical SP risk score proposed in our study is only moderate with a sensitivity of 33% and specificity of 94%, albeit comparable with other clinical scores (49,50). Finally, not unexpected, prevalences of 1 LPD SP and SSA/Ps without dysplasia were higher in the validation cohort than the derivation cohort.…”
Section: Discussionmentioning
confidence: 90%
“…Third, the SP risk score proposed in our study was developed in a reallife cohort, including symptomatic and asymptomatic patients, and hence generalizability to a screening population needs to be further examined. Fourth, the ability of identifying patients with 1 LPD SP, using the clinical SP risk score proposed in our study is only moderate with a sensitivity of 33% and specificity of 94%, albeit comparable with other clinical scores (49,50). Finally, not unexpected, prevalences of 1 LPD SP and SSA/Ps without dysplasia were higher in the validation cohort than the derivation cohort.…”
Section: Discussionmentioning
confidence: 90%
“…Many other countries, such as Australia [19], Poland [24], Hong Kong [28], Italy [29], Qatar [41], Saudi Arabia [43], Spain [52] and Sri Lanka [15] have also developed country-specific risk prediction models for colorectal cancer. When considering the global approach two models have been developed globally [27,30] while another has been developed for Asia [37].…”
Section: Questionnairementioning
confidence: 99%
“…A majority (n=35) of models include variables obtained through a questionnaire [18,19,21,22,23,24,25,26,27,28,30,33,36,37,38,39,40,41,42,43,44,45,46,49,50,51,53,54]. The questionnaires range from those with only one or two simple questions to those with detailed questions on factors such as diet, physical activity, alcohol and smoking habits and past medical facts.…”
Section: Development Of the Modelsmentioning
confidence: 99%
“…Asia-Pacific guidelines also recommend earlier screening in FDRs of CRC patients, that is, before 50 years of age [38] . A scoring system, based on several risk factors, such as age, sex, family history and smoking habit, has been developed by the Asia-Pacific Working Group for stratifying risk and prioritizing highrisk individuals for earlier screening [39] . According to this scoring system, validated in a 15-country multicenter Asian study on asymptomatic subjects, moderate-to-high-risk individuals should undergo colonoscopy, while those classified as average risk should undergo a fecal immunochemical test (FIT) followed by colonoscopy in case of a positive result [38] .…”
Section: Familial Crc Screening: When To Domentioning
confidence: 99%