The association between cardiorespiratory fitness and C-reactive protein in subjects with the metabolic syndrome

Abstract

Subjects with the metabolic syndrome who maintain a high fitness level have markedly lower CRP concentrations, as compared with those with a low fitness level.

Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults

“…These results are consistent with previous findings that hemostatic risk factors are more favorable in physically active compared with sedentary women, but that body fat, BMI, and waist circumference are important physiological predictors of these factors [47], with body fatness being a better predictor of CVD risk factor profile than aerobic fitness in healthy men [48]. Aronson et al [17] reported that subjects with the metabolic syndrome who maintain a high cardiorespiratory fitness level have markedly lower CRP concentrations as compared with those with a low fitness level. However, we did not find this association between hsCRP and cardiorespiratory fitness level, possibly because of the fact that our subjects did not have metabolic syndrome.…”

“…Furthermore, the effect of physical fitness on individuals with the metabolic syndrome is more pronounced than that in subjects without metabolic abnormalities [17]. The present study showed that exercise participants had significantly lower WHR, visceral fat area, VSR, hsCRP, fibrinogen, HbA 1c , and HOMA than nonexercise participants.…”

“…Subjects with the metabolic syndrome who maintain a high fitness level have markedly lower CRP concentrations as compared with those with a low fitness level [17]. Recent studies have shown that there is no relationship between change in CRP and the improvement in fitness and insulin sensitivity after exercise training [18,19].…”

Increased level of cardiorespiratory fitness blunts the inflammatory response in metabolic syndrome

“…Troseid et al [33] previously showed that a 12 week exercise program reduced plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome [33]. Aronson et al [34] showed that a strong inverse trend toward decreasing C-reactive protein (CRP) levels with increasing fitness levels was present in subjects in both with and without metabolic syndrome. They also showed that subjects with the metabolic syndrome who maintained a high fitness level had markedly lower CRP concentrations, as compared with those with a low fitness level.…”

The impact of cardiorespiratory fitness on inflammatory markers in patients with metabolic syndrome

“…Previously, Aronson et al [6] have also evaluated the relationship between the cardiorespiratory fitness and Creactive protein (CRP) in subjects with metabolic syndrome. They have shown a strong inverse trent toward decreasing CRP levels with increasing fitness quartiles in subjects without metabolic abnormalities, subjects with one or two metabolic abnormalities and subjects with the metabolic syndrome.…”