The association between economic development, lifestyle differentiation, and <scp>C</scp>‐reactive protein concentration within rural communities in <scp>H</scp>ainan <scp>I</scp>sland, <scp>C</scp>hina

Inoue, Yosuke; Stickley, Andrew; Yazawa, Aki; Li, Dandan; Du, Jian; Jin, Yuming; Chen, Yan; Watanabe, Chiho

doi:10.1002/ajhb.22771

Cited by 3 publications

(2 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a study undertaken in England [ 47 ], multiple aspects of the residential environment (e.g., trust, integration into the wider society, a left-wing political climate, the physical quality of the residential environment, and the unemployment rate) had a larger effect for females than males in terms of self-rated health. Inoue et al [ 52 ] also found that females were more affected by neighborhood socioeconomic characteristics (i.e., differences in the Gini coefficient) than men in terms of C-reactive protein concentration in rural China. Furthermore, while studying the French population, Vallée et al [ 53 ] suggested that females might be more influenced by the place where they live since they tend to spend more time in their community surroundings.…”

Section: Discussionmentioning

confidence: 99%

Neighborhood Characteristics and Cardiovascular Risk among Older People in Japan: Findings from the JAGES Project

et al. 2016

Self Cite

View full text Add to dashboard Cite

Previous studies have found an association between neighborhood characteristics (i.e., aspects of the physical and social environment) and the incidence of cardiovascular disease (CVD) and elevated CVD risk. This study investigated the relationship between neighborhood characteristics and CVD risk among older people in Japan where research on this association is scarce. Data came from the Japan Gerontological Evaluation Study project; questionnaire data collected from 3,810 people aged 65 years or older living in 20 primary school districts in Aichi prefecture, Japan, was linked to a computed composite CVD risk score based on biomarker data (i.e., hemoglobin A1c, systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and estimated glomerular filtration rate). A sex-stratified multilevel linear regression analysis revealed that for male participants, living in neighborhoods with a higher perceived occurrence of traffic accidents and reduced personal safety was associated with an elevated CVD risk (coefficient = 1.08 per interquartile range increase, 95% confidence interval [CI] = 0.30 to 1.86) whereas males living in neighborhoods with a higher perceived proximity of exercise facilities had a lower risk (coefficient = −1.00, 95% CI = −1.78 to −0.21). For females, there was no statistically significant association between neighborhood characteristics and CVD risk. This study suggests that aspects of the neighborhood environment might be important for CVD morbidity and mortality in Japan, particularly among men.

show abstract

Section: Discussionmentioning

confidence: 99%

Neighborhood Characteristics and Cardiovascular Risk among Older People in Japan: Findings from the JAGES Project

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…The plasma concentration of high‐sensitivity CRP (hs‐CRP) is a marker of chronic and low‐grade inflammation linked to elevated risk of CVDs (Ridker, 2003). Additionally, it has been reported that the variation in hs‐CRP is influenced by various factors, such as age and lifestyle (Inoue et al, 2016; McDade et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Association between oxidative balance score and inflammatory markers in middle‐aged and older Japanese people

Nanri,

Hara,

Nishida

et al. 2024

American J Hum Biol

View full text Add to dashboard Cite

PurposeThis study aimed to investigate the association between oxidative balance score (OBS), wherein higher OBSs indicate lower oxidative stress, and high‐sensitivity C‐reactive protein (hs‐CRP), as well as inflammatory scores, in a large cohort of Japanese adults.MethodsIn total, 9703 individuals aged 40–69 years participated in a baseline survey of a population‐based cohort study in Saga, Japan (2005–2007). OBSs were calculated from 11 prooxidant and antioxidant lifestyle factors, including dietary intake, physical activity, alcohol consumption, and smoking status. Lifestyle data, including dietary intake, were obtained using a self‐administered questionnaire. Adjusted geometric means of serum hs‐CRP levels were calculated based on OBS quartiles, and linear trend tests were performed, with adjustments for potential confounders. In addition, an inflammatory cytokine z‐score was constructed and assessed alongside individual markers.ResultsAfter adjusting for multiple confounders in both sexes, the results showed a significant inverse association between OBS and serum hs‐CRP levels in both men and women. These results remained unaltered when the OBS evaluation excluded powerful prooxidants, serum ferritin, or smoking. There was also an association between OBS and lower inflammatory z‐score, indicating reduced overall systemic inflammation.ConclusionsThese findings suggest that a higher OBS, indicating a greater predominance of antioxidants over prooxidant exposure, is associated with lower hs‐CRP levels and reduced systemic inflammation, regardless of sex.

show abstract

Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid

Rajan

Manivasagam

Dhanusu

et al. 2018

Food and Chemical Toxicology

View full text Add to dashboard Cite

The association between economic development, lifestyle differentiation, and C‐reactive protein concentration within rural communities in Hainan Island, China

Abstract: Given that CRP concentration is a marker of future CVD risk, this study suggests that within these previously homogenous rural communities, economic development might have stratified people into population subgroups with a different CVD risk.

Cited by 3 publications

References 56 publications

Neighborhood Characteristics and Cardiovascular Risk among Older People in Japan: Findings from the JAGES Project

Neighborhood Characteristics and Cardiovascular Risk among Older People in Japan: Findings from the JAGES Project

Association between oxidative balance score and inflammatory markers in middle‐aged and older Japanese people

Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid

Contact Info

Product

Resources

About