The association between frequency of e-cigarette use and long-term smoking cessation outcomes among treatment-seeking smokers receiving a behavioral intervention

Watson, Noreen L; Mull, Kristin E.; Bricker, Jonathan B.

doi:10.1016/j.drugalcdep.2020.108394

Cited by 5 publications

(7 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the iCanQuit arm, 12 Our results are consistent with 2 previous prospective RCT studies for smoking cessation. Both studies suggested that e-cigarette use impeded cigarette smoking cessation among individuals concurrently receiving a behavioral intervention for smoking cessation [15,16]. The first study used data from an RCT (n=1040) among hospitalized patients who wanted to quit combustible cigarette smoking and received cessation behavioral counseling while at the hospital [15].…”

Section: Principal Findingsmentioning

confidence: 99%

“…However, it is important to note that the authors of the review highlighted the very low certainty of these results due to imprecision and potential bias. In contrast, results from 2 prospective studies of RCTs among treatment-seeking individuals who used e-cigarettes while concurrently receiving behavioral cessation treatments suggest that e-cigarette use impedes cigarette smoking cessation [15,16]. Thus, it remains unclear whether e-cigarette use aids or hinders smoking cessation among treatment-seeking individuals while concurrently receiving behavioral support.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial

Santiago-Torres,

Mull,

Sullivan

et al. 2023

JMIR Mhealth Uhealth

View full text Add to dashboard Cite

Background Many adults use e-cigarettes to help them quit cigarette smoking. However, the impact of self-selected use of e-cigarettes on cigarette smoking cessation, particularly when concurrently receiving app-based behavioral interventions, remains unexplored. Objective This study used data from a randomized trial of 2 smartphone apps to compare 12-month cigarette smoking cessation rates between participants who used e-cigarettes on their own (ie, adopters: n=465) versus those who did not (ie, nonadopters: n=1097). Methods The study population included all participants who did not use e-cigarettes at baseline. “Adopters” were those who self-reported the use of e-cigarettes at either 3- or 6-month follow-ups. “Nonadopters” were those who self-reported no use of e-cigarettes at either follow-up time point. The primary cessation outcome was self-reported, complete-case, 30-day point prevalence abstinence from cigarette smoking at 12 months. Secondary outcomes were missing-as-smoking and multiple imputation analyses of the primary outcome, prolonged abstinence, and cessation of all nicotine and tobacco products at 12 months. In logistic regression models, we first examined the potential interaction between e-cigarette use and treatment arm (iCanQuit vs QuitGuide) on the primary cessation outcome. Subsequently, we compared 12-month cigarette smoking cessation rates between adopters and nonadopters separately for each app. Results There was suggestive evidence for an interaction between e-cigarette use and treatment arm on cessation (P=.05). In the iCanQuit arm, 12-month cigarette smoking cessation rates were significantly lower among e-cigarette adopters compared with nonadopters (41/193, 21.2% vs 184/527, 34.9%; P=.003; odds ratio 0.55, 95% CI 0.37-0.81). In contrast, in the QuitGuide arm, 12-month cigarette smoking cessation rates did not differ between adopters and nonadopters (46/246, 18.7% vs 104/522, 19.9%; P=.64; odds ratio 0.91, 95% CI 0.62-1.35). Conclusions The use of e-cigarettes while concurrently receiving an app-based smoking cessation intervention was associated with either a lower or an unimproved likelihood of quitting cigarette smoking compared to no use. Future behavioral treatments for cigarette smoking cessation should consider including information on the potential consequences of e-cigarette use. Trial Registration ClinicalTrials.gov NCT02724462; https://clinicaltrials.gov/study/NCT02724462

show abstract

Section: Principal Findingsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial

Santiago-Torres,

Mull,

Sullivan

et al. 2023

JMIR Mhealth Uhealth

View full text Add to dashboard Cite

show abstract

“…Accordingly, a more recent meta-analysis showed that EC use was only associated with quitting smoking when the device was used at least daily, and when provided as part of a smoking cessation clinical trial, rather than when used as a consumer product in observational studies [46]. In contrast, another recent study found that daily EC use was actually associated with poorer odds of quitting smoking in smokers seeking treatment [47]. Additionally, smokers using ECs who do successfully quit retain higher rates of nicotine dependency than those quitting with the assistance of drug-based therapies or non-EC nicotine replacement therapies [48].…”

Section: Human Eca Exposure Studies: Populations Of Interestmentioning

confidence: 99%

E-Cigarette Use: Device Market, Study Design, and Emerging Evidence of Biological Consequences

Snoderly

Nurkiewicz

Bowdridge

et al. 2021

IJMS

View full text Add to dashboard Cite

Electronic cigarettes are frequently viewed as a safer alternative to conventional cigarettes; however, evidence to support this perspective has not materialized. Indeed, the current literature reports that electronic cigarette use is associated with both acute lung injury and subclinical dysfunction to the lung and vasculature that may result in pathology following chronic use. E-cigarettes can alter vascular dynamics, polarize innate immune populations towards a proinflammatory state, compromise barrier function in the pulmonary endothelium and epithelium, and promote pre-oncogenic phenomena. This review will summarize the variety of e-cigarette products available to users, discuss current challenges in e-cigarette study design, outline the range of pathologies occurring in cases of e-cigarette associated acute lung injury, highlight disease supporting tissue- and cellular-level changes resulting from e-cigarette exposure, and briefly examine how these changes may promote tumorigenesis. Continued research of the mechanisms by which e-cigarettes induce pathology benefit users and clinicians by resulting in increased regulation of vaping devices, informing treatments for emerging diseases e-cigarettes produce, and increasing public awareness to reduce e-cigarette use and the onset of preventable disease.

show abstract

“…The results of these studies have been mixed. Some studies found a positive association between e-cigarette use and cigarette smoking cessation or reduction,1–4 6 9–14 20 while others found either a non-significant or negative association 5 7 8 15–19 21 22. The inconsistent results could be partially caused by different study designs 26–29.…”

Section: Introductionmentioning

confidence: 98%

“…Given the growing popularity of electronic cigarettes (e-cigarettes), it is essential to understand their public health impact, especially their effect on cigarette abstinence. Many studies—including randomised controlled trials (RTCs),1–5 cross-sectional studies6–8 and longitudinal cohort studies9–22—have examined the role of e-cigarette use in cigarette smoking cessation 23–27. The results of these studies have been mixed.…”

Section: Introductionmentioning

confidence: 99%

Changes in e-cigarette use and subsequent cigarette smoking cessation in the USA: evidence from a prospective PATH study, 2013–2018

2022

View full text Add to dashboard Cite

AimsTo examine the relationship between changes in electronic cigarette (e-cigarette) use and subsequent cigarette smoking cessation.MethodsUsing data from the Population Assessment of Tobacco and Health Study (wave 1–wave 4), we analysed a study cohort of 3014 current adult cigarette smokers at wave 1 who tried to quit during the past 12 months. We categorised changes in e-cigarette use from wave 1 to wave 2 as: daily initiation, non-daily initiation, increase to daily use, increase to non-daily use, stable daily use, stable non-daily use, decrease from daily use, quit non-daily use and non-use. We estimated multivariable logistic regressions on short-term (≥1 month and <12 months) cigarette smoking cessation at wave 3 and long-term (≥12 months) cigarette smoking cessation at wave 4. We conducted sensitivity analyses using alternative study cohorts.ResultsAmong the study cohort, 2.4% initiated daily, 7.5% initiated non-daily, 1.0% increased to daily, 1.4% increased to non-daily, 1.5% maintained daily, 3.0% maintained non-daily, 2.4% decreased from daily and 3.8% quit non-daily e-cigarette use between waves 1 and 2; 7.9% and 6.9% reported short-term and long-term cigarette smoking cessation. 15.1% of short-term and 16.3% of long-term cigarette quitters used e-cigarettes. Compared with non-users, smokers who initiated daily, increased to daily or quit non-daily e-cigarette use between waves 1 and 2 had higher odds of short-term cigarette smoking cessation at wave 3. These results are robust to different study cohort specifications.ConclusionThe findings suggest a complex relationship between changes in e-cigarette use and subsequent cigarette smoking cessation.

show abstract

The association between frequency of e-cigarette use and long-term smoking cessation outcomes among treatment-seeking smokers receiving a behavioral intervention

Cited by 5 publications

References 42 publications

Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial

Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial

E-Cigarette Use: Device Market, Study Design, and Emerging Evidence of Biological Consequences

Changes in e-cigarette use and subsequent cigarette smoking cessation in the USA: evidence from a prospective PATH study, 2013–2018

Contact Info

Product

Resources

About