The association between health-related quality of life and mortality among hemodialysis patients

Kušleikaitė, Neda; Bumblytė, Inga Arūnė; Kuzminskis, Vytautas; Vaičiūnienė, Rūta

doi:10.3390/medicina46080076

Cited by 26 publications

(25 citation statements)

References 20 publications

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“…[1][2][3] Poorer health-related quality of life (HRQOL) is associated with increase in morbidity and mortality among patients. 4,5 Previous studies reported that HRQOL depends on treatment modality. 6,7 Thus, the transplant recipients scored better quality of life in comparison with hemodialysis (HD) and peritoneal dialysis patients.…”

Section: Introductionmentioning

confidence: 99%

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Knežević¹,

Djordjević²,

Radovanovic-Velickovic³

et al. 2012

Renal Failure

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Background: The quality of life in patients undergoing hemodialysis is significantly disturbed. There are data that hemodiafiltration (HDF) may be more effective than conventional hemodialysis in the removal of uremic toxins and may reduce frequency and severity of intradialytic and postdialysis adverse symptoms in patients. Also, some researchers suggest advantages of using high-flux membranes compared with low-flux. Objective: The aim of this study was to examine whether hemodialysis modality and membrane flux, independent of membrane biocompatibility, make differences in quality of life in patients. Methods: In our cross-sectional study, we evaluated 124 patients who were divided, based on therapy, into three groups: online HDF, high-flux hemodialysis, and low-flux hemodialysis. Data were collected using the Short Form-36 questionnaire combined with special questionnaire, which included demographic and clinically related questions. Results: Health-related quality of life was better in patients on HDF compared with patients on hemodialysis, especially compared with low-flux hemodialysis patients in most of the scales and in both dimensions: physical component scale and mental component scale. There were no statistically significant differences in Short Form-36 domains between high-flux hemodialysis and low-flux hemodialysis. Conclusion: Our data suggest the potential advantages of HDF with regard to influence on quality of life, which is sufficient to justify further research in prospective and longitudinal study design.

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Section: Introductionmentioning

confidence: 99%

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Knežević¹,

Djordjević²,

Radovanovic-Velickovic³

et al. 2012

Renal Failure

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“…Education level also affected depression levels and recipients with higher educational backgrounds appeared to be less depressed. It has been found that the severity of depressive symptoms is higher among recipients with lower educational status [9]. There are significant differences in depression between male and female recipients.…”

Section: Research Aimsmentioning

confidence: 89%

“…There is consensus on the significance of psychosocial factors in influencing life after transplant [9][10][11][12][13]. The positive and negative impact of a multitude of psychosocial conditions such as anxiety and uncertainty about future, coping with challenges of transplant is analysed to understand the subjective factors in transplant experience.…”

Section: Research Aimsmentioning

confidence: 99%

Depression Doubles Mortality Risk among Transplant Recipients

Kamran¹

2014

Int J Sch Cog Psychol

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“…In addition, Čengić et al () suggested that relying on haemodialysis to sustain life makes patients feel like “prisoners” in their homes, and reduced physical and mental activities make them feel useless and inferior; only employed patients regarded dialysis as “an extra task.” Patients who are still working may also have a relatively better physical condition and working abilities, which may provide them with better opportunities to obtain social support and facilitate their return to society. Kušleikaitė et al () suggested that the degree of social regression might be an important factor affecting HRQOL among patients on haemodialysis, and noted HRQOL was closely related to hospitalisation rate and mortality. In addition, unemployed patients have lost their stable financial income, which increases the burden on patients and their families and may lead to changes in family structure.…”

Section: Discussionmentioning

confidence: 99%

The health‐related quality of life among patients on maintenance haemodialysis: Evaluation using the “EQ‐5D”

Yuan

Yang

Zhang

et al. 2019

Journal of Clinical Nursing

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Purpose We conducted a cross‐sectional investigation of health‐related quality of life (HRQOL) among maintenance haemodialysis (MHD) patients, and determined important predictive factors of HRQOL in these patients. Methods Psychological factors were evaluated with the Hospital Anxiety and Depression Scale (HADS), the Pittsburgh Sleep Quality Index (PSQI) and the General Self‐Efficacy Scale (GSES). HRQOL was evaluated with the EQ‐5D. Laboratory data (albumin, haemoglobin and C‐reactive protein) were collected for medical evaluation. We also collected participants’ demographic data, including gender, age, et al. This study was in compliance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist. Results The mean EQ‐5D score was 0.86 ± 0.12, mean HADS‐anxiety score was 5.27 ± 3.41, mean HADS‐depression score was 5.29 ± 3.58, mean PSQI score was 7.00 ± 4.23 and mean GSES score was 6.86 ± 2.03. Participants’ mean haemoglobin was 108.18 ± 16.45 g/L, mean albumin was 41.80 ± 4.61 g/L and mean C‐reactive protein was 8.88 ± 18.50 mg/L. HRQOL was negatively correlated with HADS‐anxiety (r = −0.390, p < 0.001), HADS‐depression (r = −0.385, p < 0.001), PSQI (r = −0.285, p < 0.001) and C‐reactive protein (r = −0.198, p = 0.034). HRQOL was positively correlated with GSES (r = 0.205, p = 0.007). Age (p < 0.001), anxiety (p < 0.001), depression (p = 0.002), and postdialysis unemployment (p < 0.001) were independent risk factors for HRQOL. Conclusion Different health interventions should be implemented to improve patients’ HRQOL. Relevance to clinical practice The results will provide evidence for establishing healthcare interventions to maintain or improve HRQOL among this patient population.

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The association between health-related quality of life and mortality among hemodialysis patients

Cited by 26 publications

References 20 publications

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Depression Doubles Mortality Risk among Transplant Recipients

The health‐related quality of life among patients on maintenance haemodialysis: Evaluation using the “EQ‐5D”

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