The Association Between Lipid Serum and Semen Parameters: a Systematic Review

Pakpahan, Cennikon; Rezano, Andri; Margiana, Ria; Amanda, Bella; Agustinus, Agustinus; Darmadi, Darmadi

doi:10.1007/s43032-022-01040-8

Cited by 10 publications

(3 citation statements)

References 60 publications

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“…Therapy Plan for Several Sessions such as testosterone within normal, so testosterone decline induced erectile dysfunction can be excluded.6 Based on this factor, we diagnose this patient with psychogenic erectile dysfunction. 7 In this patient, we hypothesize that there were disturbances in the emotional and motivational parts of the brain that interfere with the erection process in these patients. The anamnesis that plays an important role is the history of sexual development in the past, where he lost his father figure when he was young and his senior who invited to have a same-sex sexual relations in college.…”

Section: Consolidation Training and Maintenancementioning

confidence: 87%

“…Sexual therapeutic approach is one of the main treatments of psychogenic erectile dysfunction. 7 Ego-dystonic sexual orientation described as gender identity or sexual preference that is not in doubt, but the individual wishes it were different because of associated psychological and behavioral disorders and may seek treatment to change it. This patient can be classified into ego-dystonic homosexual because: (1).…”

Section: Consolidation Training and Maintenancementioning

confidence: 99%

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A Case Report of Psychogenic Erectile Dysfunction with Ego Dystonic Sexual Disorientation: Is Still Relevant to Treat?

Laurus

Pakpahan

William

et al. 2023

IABJ

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Background: Converting Ego-dystonic homosexual to heterosexual is still controversial. homosexuals are encouraged to be accepted and do not require conversion. Currently, many cases of homosexuals are required to accept their identity and do not require conversion. However, there are times when patients want to be heterosexual and experience sexual dysfunction because of this orientation. Then, how a medical professional deal with such a case especially in the era of ease of information and technology? Choose to demand that the patient accept their sexual orientation or help the patient to become heterosexual. Objective: Here we present the case of a man, 44 years old, with a psychogenic erection with ego-dystonic homosexual disorientation, along with a review of the literature related to the case. Method: A case report with literature review Case/Result: We report 44-year-old man who has been married for six years complains of difficulty and decreased erection for 5.5 years. This man had a history of sexual intercourse with men during college but decided to become a heterosexual man and married his current wife. For the first six months, the patient performed oral sex with his wife. Then afterwards, the patient has difficulty getting an erection and even fails. The patient feels guilty toward his wife until their relationship becomes a crisis. The patient wants to commit to being a heterosexual man. So, the patient came to the andrology clinic for therapy. We applied intersystemic assessment approach to the patient. There is progress in the patient’s condition until now. Conclusion: Many experts say that homosexuality should be accepted and should not be converted. But in the end, the choice is returned to the patient, whether to choose to convert or not. Physicians only need to support the patient's therapy and choices so that he does not experience any mental disorders that ultimately endanger his life. Keywords: , , , ,

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Section: Consolidation Training and Maintenancementioning

confidence: 87%

Section: Consolidation Training and Maintenancementioning

confidence: 99%

A Case Report of Psychogenic Erectile Dysfunction with Ego Dystonic Sexual Disorientation: Is Still Relevant to Treat?

Laurus

Pakpahan

William

et al. 2023

IABJ

View full text Add to dashboard Cite

show abstract

“… 11 , 12 Catalase (CAT, Cat num: A007-1), superoxide dismutase (SOD, Cat num: A001-1) and malondialdehyde (MDA, Cat num: A003-1) were measured by spectrophotometry. 13 , 14 …”

Section: Methodsmentioning

confidence: 99%

Is Lipopolysaccharide-Induced Lipid Metabolism Disorder in Testis of Rats a Consequence of Plasma Lipid Changes?

Zheng,

Li,

Shang

et al. 2024

JIR

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Purpose The systemic infection and inflammation can result in testes injury, whereas the exact mechanism is unknown. The lipid metabolism has a dual impact on controlling metabolism and inflammation, which is a potential pathway. The objective of this study was to determine if changes in plasma lipids during lipopolysaccharide (LPS)-induced systemic inflammation affect the dysregulation of testes lipid metabolism. Materials and Methods LPS (5 mg/kg) was used to induce systemic inflammation in rats after a single intraperitoneal injection. After 4 weeks, the rats were sacrificed, and the serum and testes were used for laboratory measurements and histology examination. Plasma and testis were used for lipidomics analysis based the liquid chromatography-mass spectrometry. Spearman rank correlation analysis was used to compare the correlation of differential lipids in phospholipids, glycerolipids, and sphingolipids between testis and plasma. Results LPS raised the levels of cytokines in serum and testis, decreased the activities of antioxidant enzymes, increased the levels of lipid peroxidation products, and damaged testis tissue. In testis and plasma, 146 and 401 differential lipids, mostly phosphatidylcholine, phosphatidylethanolamine an so on, were found in comparison to the control group. Correlation analysis produced a total of 2528 correlation coefficients, 1150 of which were P<0.05 and accounted for 45.49%. Conclusion The changes of lipid composition and content in the testis are related to cytokine overload and oxidative stress. Testis lipid metabolism disorders caused by LPS-induced systemic inflammation are lack of a correlation with plasma lipid changes, and are likely owing to interference with the testis itself.

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Impact of metabolic syndrome factors on sperm DNA fragmentation in males from infertile couples: A systematic review and meta-analysis

Mulya,

Hasan,

Iqhrammullah

2024

Journal of Gynecology Obstetrics and Human Reproduction

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The Association Between Lipid Serum and Semen Parameters: a Systematic Review

Cited by 10 publications

References 60 publications

A Case Report of Psychogenic Erectile Dysfunction with Ego Dystonic Sexual Disorientation: Is Still Relevant to Treat?

A Case Report of Psychogenic Erectile Dysfunction with Ego Dystonic Sexual Disorientation: Is Still Relevant to Treat?

Is Lipopolysaccharide-Induced Lipid Metabolism Disorder in Testis of Rats a Consequence of Plasma Lipid Changes?

Impact of metabolic syndrome factors on sperm DNA fragmentation in males from infertile couples: A systematic review and meta-analysis

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