Background: Self-care behavior is crucial for patients with heart failure to have positive outcomes, and it also serves as a predictor of wellbeing. The self-care tasks that these patients are required to carry out include managing their symptoms, sticking to numerous pharmaceutical regimens, following dietary salt restrictions, and self-monitoring weight. In many cases, a crucial aspect of heart failure treatment is still challenging. Objective: To determine the self-care practices of patients with heart failure at Hasan Sadikin General Hospital in Bandung, Indonesia. Methods: The study used a descriptive study with a consecutive sampling of 196 patients with heart failure in the clinic. Results: the demographic characteristics were mean of age (in year) 56.26 ± 12.49, majority were male 144 respondents (73.57%), above the senior high school 128 respondents (65.3%), New York Heart Association NYHA II category 76 respondents (38.8%), NYHA III category at 92(46.9%), NYHA IV category at 28(14.3%), EF 33.65±9.311, length of HF 2.02± 1.08, BMI 25.48±1.98, total score of self-care behaviour 88.35±7.736. The score of the subvariable of self-care behavior is as follows: consulting behaviors 19.68±2.405, dietary behaviors 8.16 ± 1.207, symptom perception 21.93 ±2.188, symptom recognition 9.65 ±1.393, self-care management 8.64±0.853, problem-solving behaviors 4.64±1.278, self-efficacy 20.20 ±1.979. Conclusion: Patients with heart failure exhibit poor self-care behavior; hence, nurse practitioners' involvement is required to promote self-care behavior among patients with heart failure.