The association between Schistosoma Haematowum infection and heavy proteinuria

Parasitic Kidney Disease: Milestones in the Evolution of Our Knowledge

“…15,16 An epidemiologic study from Upper Egypt documented the occurrence of a transient immune-mediated acute glomerular injury in patients exposed to new S haematobium infection. 17 The same also was reported in sporadic cohorts, 18 which seems to indicate that S haematobium glomerulopathy is relatively uncommon compared to Schistosoma mansoni (discussed later), of little clinical significance, and selflimited.…”

The Merits of Urine Color Observation as a Rapid Diagnostic Technique to Estimate Schistosoma Haematobium Infection in Two Endemic Areas of Benue State, Nigeria

“…Although, at the present time the precise origin and clinical significance of the proteinuria observed in S. haematobium infection remains unknown (Elissa, 2004). Nonetheless Sabour et al (1972), Ezzat et al (1974 andEzzat et al (1978) claimed an association between glomerulonephritis, the inflammation of the membrane tissue of the kidney and S. haematobium in human. Chugh and Sakuja (1990) reported that glomurelonephritis is highly prevalent in areas of the tropic where urinary schistosomiasis is also common, however its relationship to S. haematobium remain unclear.…”

The Kidney in Schistosomiasis

“…Uncomplicated residual hepatic fibrosis in the recipient does not seem to significantly modify the pharmacokinetics of the immunosuppressive agents used in transplant recipients. However, variations in cyclosporine blood levels have been noted 15 and attributed to altered absorption of the drug. Associated viral hepatitis may have a considerable impact on the protocols of donor selection and prophylactic immunosuppression and on the eventual outcome (see Chapters 98 and 101).…”

“…S. haematobium GN is rare and usually subclinical, but a small epidemic of acute nephritis was reported in an Egyptian village where the infection had been recently introduced as a result of change in the agricultural irrigation system. 15 Schistosomal gut antigens are present in circulating immune complexes as well as in the immune deposits in mesangial, subendothelial, and intramembranous locations. The presence of …”