The association between smoking and hypertension in a population-based sample of Vietnamese men

Thuy, Au Bich; Blizzard, Leigh; Schmidt, Michael D.; Luc, Pham Hung; Granger, Robert; Dwyer, Terence

doi:10.1097/hjh.0b013e32833310e0

Cited by 81 publications

(59 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Meanwhile, hypertension and smoking coexist more often than expected, which further amplifies risk of the CVD mortality [34,35]. Our previous study based on the same dataset revealed that there existed a synergistic interaction on an additive scale between current smoking and high SBP (140 mmHg) for the risk of coronary heart disease (CHD) in female adult population [36].…”

Section: Discussionmentioning

confidence: 95%

Does cigarette smoking exacerbate the effect of blood pressure on the risk of cardiovascular and all-cause mortality among hypertensive patients?

Hao

Cao

et al. 2012

Journal of Hypertension

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 95%

Does cigarette smoking exacerbate the effect of blood pressure on the risk of cardiovascular and all-cause mortality among hypertensive patients?

Hao

Cao

et al. 2012

Journal of Hypertension

View full text Add to dashboard Cite

show abstract

“…[15][16][17][18][19] There are few studies investigating the relationship between SHS exposure and BP among never smokers. A cross-sectional study involving clinically normotensive passive smokers found that selfreported passive smoking was associated with increased levels of BP in a dose-related manner.…”

Section: Discussionmentioning

confidence: 99%

Association of Serum Cotinine Levels and Hypertension in Never Smokers

2013

View full text Add to dashboard Cite

Seated systolic and diastolic BPs were measured using a mercury sphygmomanometer according to the American Heart Association and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). 13,14 Up to 3 measurements were averaged for systolic and diastolic pressures. Patients were considered hypertensive if they reported physician diagnosis of hypertension, current BP-reducing medication use, or had systolic BP ≥140 mm Hg and diastolic BP ≥90 mm Hg based on JNC 7 criteria. 13Abstract-Hypertension is a major public health problem. Identifying novel risk factors for hypertension, including widely prevalent environmental exposures, is therefore important. Active smoking is a well-known risk factor for hypertension and cardiovascular diseases. However, there are no studies investigating the relationship between secondhand smoke exposure, measured objectively by serum cotinine, and high blood pressure among never smokers. We examined 2889 never smokers from the National Health and Nutrition Examination Survey 2005-2008. Our exposure of interest was secondhand smoke exposure among never smokers, estimated by serum cotinine level, and our main outcome was hypertension (n=1004). We found that in never smokers, higher serum cotinine levels were positively associated with hypertension. In comparison with those with serum cotinine levels ≤0.025 ng/mL, the multivariable odds ratio (95% confidence interval) of hypertension among those with serum cotinine levels ≥0.218 ng/mL was 1.44 (1.01-2.04). In addition, higher serum cotinine was positively associated with mean change in systolic blood pressure (odds ratio [95% confidence interval], 3.24 [0.86-5.63]; P=0.0061). However, no association was present with diastolic blood pressure. In conclusion, in never smokers, higher secondhand smoke exposure measured objectively by serum cotinine levels was found to be associated with systolic blood pressure and hypertension independent of age, sex, ethnicity, education, alcohol drinking, body mass index, glycohemoglobin, total cholesterol, and other confounders. Briefly, the serum sample was spiked with methyl-D3 cotinine as an internal standard, and after an equilibration period, the sample was applied to a basified solid-phase extraction column. Cotinine was extracted off the column with methylene chloride, the organic extract was concentrated, and the residue was injected onto a short, C18 high-performance liquid chromatography column. The eluant from these injections was monitored by atmospheric pressure chemical ionization-tandem mass spectrometry, and the m/z 80 daughter ion from the m/z 177 quasimolecular ion was quantitated, along with additional ions for the internal standard, external standard, and for confirmation. Cotinine concentrations were derived from the ratio of native/labeled cotinine in the sample, by comparisons to a standard curve. Detailed description of serum cotinine measurement in NHANES is available online.12 Serum total cholesterol was...

show abstract

“…Although a clinically relevant effect of cigarette smoking on in-office blood pressure (BP) is controversial [1][2][3][4][5][6][7][8][9][10][11][12][13][14], as patients may refrain from smoking prior to office visits and cigarette smoking has relatively short-lived effects on BP [15][16][17][18][19], the major clinical impact of smoking on BP may not be accurately captured by in-office BP measurements. Indeed, despite a lack of relationship between smoking and in-office BP, a relationship between current smoking and out-of-office (24-h) BP has been reported on [20][21][22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Relationship of predominantly mild current smoking to out-of-office blood pressure in a community sample in Africa

Woodiwiss

Scott

Maseko

et al. 2011

Journal of Hypertension

View full text Add to dashboard Cite

show abstract

The association between smoking and hypertension in a population-based sample of Vietnamese men

Abstract: In this population-based sample, hypertension was associated with smoking in a dose-response manner when characterized as number of years of smoking and lifetime cigarette consumption, but was not associated with current smoking status.

Cited by 81 publications

References 36 publications

Does cigarette smoking exacerbate the effect of blood pressure on the risk of cardiovascular and all-cause mortality among hypertensive patients?

Does cigarette smoking exacerbate the effect of blood pressure on the risk of cardiovascular and all-cause mortality among hypertensive patients?

Association of Serum Cotinine Levels and Hypertension in Never Smokers

Relationship of predominantly mild current smoking to out-of-office blood pressure in a community sample in Africa

Contact Info

Product

Resources

About