2023
DOI: 10.1002/cnr2.1782
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The association of blood ctDNA levels to mutations of marker genes in colorectal cancer

Abstract: Background Colorectal cancer (CRC) is a deadly and commonly diagnosed cancer. Cell‐free circulating tumor DNAs (ctDNA) have been used in the diagnosis and treatment of CRC, but there are open questions about the relationship between ctDNAs and CRC. Although mutations of genes detected by ctDNA in CRC have been studied, the quantitative relationship between ctDNA mutations and ctDNA concentration has not been addressed. Aims We hypothesized that there was an association between mutations of genes identified in … Show more

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