The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period

Crema, Michel D.; Guermazi, Ali; Li, L.; Nogueira-Barbosa, Marcello Henrique; Marra, Monica; Roemer, Frank W.; Eckstein, F.; Graverand, M.-P. Hellio Le; Wyman, Bradley T.; Hunter, David J.

doi:10.1016/j.joca.2009.11.003

Cited by 91 publications

(81 citation statements)

References 38 publications

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“…The association between MR imaging or arthroscopically detected meniscal disease and cartilage loss within the same tibiofemoral joint has been reported (24)(25)(26). Moreover, an arthroscopic study showed that, compared with bucket-handle and/or vertical tears of the medial meniscus, root tears were associated with more severe medial tibiofemoral cartilage damage (26).…”

Section: Musculoskeletal Imaging: Medial Posterior Meniscal Root Tearmentioning

confidence: 97%

Medial Posterior Meniscal Root Tears Are Associated with Development or Worsening of Medial Tibiofemoral Cartilage Damage: The Multicenter Osteoarthritis Study

Guermazi

Hayashi²,

Jarraya³

et al. 2013

Radiology

113

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MPH Purpose:To assess the association of meniscal root tear with the development or worsening of tibiofemoral cartilage damage. Materials and Methods:Institutional review board approval and written informed consent from all subjects were obtained. A total of 596 knees with radiographically depicted osteoarthritis were randomly selected from the Multicenter Osteoarthritis study cohort. Cartilage damage was semiquantitatively assessed by using the Whole-Organ Magnetic Resonance Imaging Score (WORMS) system (grades 0-6). Subjects were separated into three groups: root tear only, meniscal tear without root tear, and neither meniscal nor root tear. A log-binomial regression model was used to calculate the relative risks for knees to develop incident or progressing cartilage damage in the root tear group and the meniscal tear group, with the no tear group serving as a reference. Results:In the medial tibiofemoral joint, there were 37 knees with isolated medial posterior root tear, 294 with meniscal tear without root tear, and 264 without meniscal or root tear. There were only two lateral posterior root tears, and no anterior root tears were found. Thus, the focus was on the medial posterior root tear. Conclusion:Isolated medial posterior meniscal root tear is associated with incident and progressive medial tibiofemoral cartilage loss.q RSNA, 2013

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Section: Musculoskeletal Imaging: Medial Posterior Meniscal Root Tearmentioning

confidence: 97%

Medial Posterior Meniscal Root Tears Are Associated with Development or Worsening of Medial Tibiofemoral Cartilage Damage: The Multicenter Osteoarthritis Study

Guermazi

Hayashi²,

Jarraya³

et al. 2013

Radiology

113

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“…There is a strong rationale, therefore, to preserve as much menis cus tissue as possible when treating patients with trau matic tears, horizontal tears and/or intra meniscal sig nal changes on MRI, as the preserved tissue might pro vide sub stantial meniscal function. 95 The bio mechanical effect of loss of meniscal function is well docu mented in multi ple biomechanical studies. [31][32][33][34][35][36] Cartilage loss predomi nantly occurs in the vicinity of the meniscus dam age, suggesting a strong cause and effect relationship between the damage and structural progression of OA.…”

Section: Menisci Anatomy and Functionmentioning

confidence: 99%

Meniscus pathology, osteoarthritis and the treatment controversy

et al. 2012

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The menisci are internal structures that are of central importance for a healthy knee joint; they have a key role in the structural progression of knee osteoarthritis (OA), and the risk of the disease dramatically increases if they are damaged by injury or degenerative processes. Meniscus damage might be considered a signifying feature of incipient OA in middle-aged and elderly people. As approximately every third knee of people in these groups has a damaged meniscus, tears are common incidental findings of knee MRI. However, as most tears do not cause symptoms, careful clinical evaluation is required to determine if a damaged meniscus is likely to directly impact a patient's symptoms. Conservative management of patients with knee pain and a degenerative meniscal tear should be considered as a first-line therapy before surgical treatment is contemplated. Patients with mechanical interference of joint movements, such as painful catching or locking, might need surgical treatment with meniscal repair if possible. In a subset of patients, meniscal resection might relieve pain and other symptoms that potentially originate directly from the torn meniscus. However, the possibility of an increased risk of OA if functional meniscal tissue is removed cannot be overlooked.

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“…While meniscal extrusion was associated with a greater progression of tibiofemoral cartilage defects over 6 months in subjects with chronic knee pain [32 && ], prevalent single meniscal tears and meniscal maceration were also associated with increased loss of cartilage thickness over 2 years in women over 40 years [35]. The detrimental effects of meniscal tears on loss of cartilage thickness were subregion specific, suggesting a focal protective role of meniscal tissue on articular cartilage integrity in knee osteoarthritis [36].…”

Section: Meniscal Lesionsmentioning

confidence: 99%

Use of imaging techniques to predict progression in osteoarthritis

Ding

Zhang

Hunter

2013

Current Opinion in Rheumatology

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The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period

Abstract: The protective function of the meniscus appears to be preserved in the presence of intrasubstance meniscal signal changes. Prevalent single tears and meniscal maceration were found to be associated with increased cartilage loss in the same compartment, especially at the PH.

Cited by 91 publications

References 38 publications

Medial Posterior Meniscal Root Tears Are Associated with Development or Worsening of Medial Tibiofemoral Cartilage Damage: The Multicenter Osteoarthritis Study

Medial Posterior Meniscal Root Tears Are Associated with Development or Worsening of Medial Tibiofemoral Cartilage Damage: The Multicenter Osteoarthritis Study

Meniscus pathology, osteoarthritis and the treatment controversy

Use of imaging techniques to predict progression in osteoarthritis

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