The Associations of Floppy Eyelid Syndrome: A Case Control Study

Ezra, Daniel G.; Beaconsfield, Michele; Sira, Mano; Bunce, Catey; Wormald, Richard; Collin, Richard

doi:10.1016/j.ophtha.2009.09.029

Cited by 90 publications

(87 citation statements)

References 55 publications

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“…Muayenede s›kl›kla kapakta gevfleklik, papiller konjonktivit, punktat epitelyal keratopati, kirpik pitozis ve konjonktival hiperemi saptan›r. Bunun d›fl›nda, dermatoflalazis, blefaropitozis, ektropiyon ve keratokonus GGS'lu hastalarda normal bireylere k›yasla daha s›kt›r (2)(3)(4)(5).…”

Section: Giriflunclassified

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Floppy Eyelid Syndrome: Clinical Findings and Results of Lateral Pentagonal Eyelid Resection

Oral¹,

Çiftçi²,

Gündüz³

et al. 2010

tjo

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ÖzetAmaç: Gevflek gözkapa¤› sendromlu hastalar›n demograf›k ve klinik özelliklerini sunmak ve tam kat beflgen rezeksiyon yön-temiyle gözkapa¤› k›saltman›n sonuçlar›n› gözden geçirmek. Result: Fifty-eight upper eyelids of 30 patients (mean age, 59 years) were included in the study. Irritation (93%) and epiphora (79%) were the most common presenting symptoms. Based on body mass index, 20 patients (67%) were obese and 19 patients (63%) had a history of obstructive sleep apnea. After surgery, ocular surface symptoms significantly resolved or decreased in all eyes. In 1 eye (4%), in which ocular complaints recurred, a secondary eyelid shortening procedure was required for residual lid laxity 12 months after the first surgery. Follow-up time ranged from 2 to 37 months (mean, 15 months). Discussion:The results of this study support the idea that obesity and/or sleep apnea syndrome occur more frequently in patients with floppy eyelid syndrome and eyelid shortening with lateral pentagonal resection is an effective treatment method. (Turk J Ophthalmol 2010; 40: 333-7)

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Section: Giriflunclassified

“…Hastalar›n ço¤u erkektir ve orta yafl›n üstündedir (5)(6)(7)(8). Tedavi için baz› medikal yöntemler önerilmekle birlikte, hastalar›n ço¤unda kapak gevflekli¤inin cerrahi olarak düzeltilme-si gerekir.…”

Section: Giriflunclassified

Floppy Eyelid Syndrome: Clinical Findings and Results of Lateral Pentagonal Eyelid Resection

Oral¹,

Çiftçi²,

Gündüz³

et al. 2010

tjo

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“…Urrets-Zavalia syndrome, an uncommon postoperative complication of PKP, has also been associated with keratoconus, which suggests an intrinsic abnormality in irises with this disease (10) . Others have described an association between keratoconus and floppy eyelids (11,12) . Thus, multiple lines of evidence indicate extracorneal manifestations of keratoconus involving the iris and/or the periocular skin and connective tissues.…”

Section: Introductionmentioning

confidence: 98%

Quantitative analysis of iris parameters in keratoconus patients using optical coherence tomography

Bonfadini¹,

Arora²,

Vianna³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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Purpose: To investigate the relationship between quantitative iris parameters and the presence of keratoconus. Methods: Cross-sectional observational study that included 15 affected eyes of 15 patients with keratoconus and 26 eyes of 26 normal age-and sex-matched controls. Iris parameters (area, thickness, and pupil diameter) of affected and unaffected eyes were measured under standardized light and dark conditions using anterior segment optical coherence tomography (AS-OCT). To identify optimal iris thickness cutoff points to maximize the sensitivity and specificity when discriminating keratoconus eyes from normal eyes, the analysis included the use of receiver operating characteristic (ROC) curves. Results: Iris thickness and area were lower in keratoconus eyes than in normal eyes. The mean thickness at the pupillary margin under both light and dark conditions was found to be the best parameter for discriminating normal patients from keratoconus patients. Diagnostic performance was assessed by the area under the ROC curve (AROC), which had a value of 0.8256 with 80.0% sensitivity and 84.6% specificity, using a cutoff of 0.4125 mm. The sensitivity increased to 86.7% when a cutoff of 0.4700 mm was used. Conclusions: In our sample, iris thickness was lower in keratoconus eyes than in normal eyes. These results suggest that tomographic parameters may provide novel adjunct approaches for keratoconus screening.

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“…Several other systemic conditions have already been associated with FES, such as diabetes, ischemic heart disease, hypercholesterolemia, osteoarthritis, asthma, gastroesophageal reflux disease, chronic renal failure, and schizophrenia (22) . However, many of these conditions are directly or indirectly linked with obesity, which may represent a confounding factor.…”

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confidence: 99%

Floppy eyelid syndrome: review

Miyamoto¹,

Santo²,

Roisman³

et al. 2011

Arq. Bras. Oftalmol.

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RESUMOA síndrome de frouxidão palpebral é caracterizada pela fácil eversão da pálpebra que ocorre espontaneamente durante o sono causando exposição dos olhos, com consequente conjuntivite papilar crônica. Sua patogênese ainda não está totalmente definida e é mais comum em pacientes masculinos, obesos, de meia idade e está associada a doenças sistêmicas como apnéia obstrutiva do sono, hipertensão arterial e diabetes. Quando o tratamento clínico não apresenta boa resposta, procedimentos cirúrgicos apresentam bons resultados, com técnicas em constante evolução.Descritores: Conjuntiva/patologia; Conjuntivite; Ectrópio; Obesidade/complicações; Hipertensão/complicações; Diabete Mellitus/complicações; Apnéia do sono tipo obstrutiva/complicações; Doenças palpebrais/cirurgia; Síndrome; Músculos oculomotores/cirurgia; Pálpebras/cirurgia; Doenças da córnea ABSTRACTFloppy eyelid syndrome is characterized by the easy evertion of the upper eyelid which occurs spontaneously during the sleep, causing the exposure of the eye surface and chronic papillary conjunctivitis. Its pathogenesis is not totally defined yet: it is usually more frequent in middle-aged, male obese patients and it is associated with systemic disorders such as obstructive sleep apnea, high blood pressure and diabetes. On the occasions which conservative treatment fails, surgical procedures present good results, including surgical techniques which are constantly evolving.

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The Associations of Floppy Eyelid Syndrome: A Case Control Study

Cited by 90 publications

References 55 publications

Floppy Eyelid Syndrome: Clinical Findings and Results of Lateral Pentagonal Eyelid Resection

Floppy Eyelid Syndrome: Clinical Findings and Results of Lateral Pentagonal Eyelid Resection

Quantitative analysis of iris parameters in keratoconus patients using optical coherence tomography

Floppy eyelid syndrome: review

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