The aura of malignant tumor

Abstract

The global incidence of pyogenic liver abscess (PLA) is increasing, but related reports of malignant tumor-related PLA are infrequent. Potential malignant tumors of PLA have been reported, but there is no relevant predictive model for this subsection of patients. To explore the risk factors of malignant tumor-related PLA. A retrospective analysis about a total of 881 patients who had been diagnosed with PLA from January 2005 to May 2018 was performed. The incidence of malignant tumor-related PLA in the study was 9.99% (88/881) out of all PLA cases. And that of potential malignant tumors with PLA was 4.65% (41/881). There were 62 patients with malignant tumor-related PLA in the observation group, while 146 cases without malignant tumor-related PLA were considered as control group. The data from 52 cases of malignant tumor and nonmalignant tumor-related PLA was verified. The malignant tumor type was mainly hepatobiliary malignant tumor, which occupies 72.3% (45/62) in all malignant tumor related PLA cases used to the model. Compared with nonmalignant tumor group, the rate of ineffective and mortality was higher in the malignant tumor group [19.4%(12/62) vs 7.5%(11/148), P = .01]. Multivariate analysis suggested that hepatobiliary interventional therapy or surgery, hepatitis B virus infection, multiple abscesses, portal embolism, and bile duct dilatation were independent risk factors for potential malignant tumors within the patients who combined with PLA. PLA could be considered as an early warning sign of potential malignant tumors. Malignant tumor-related PLA had a poor prognosis. Patients with PLA who have more than one independent risk factor or logit( P ) > −1.694 may be considered as the high risk group for potential hepatobiliary or colorectal malignant tumors.

ThereAdoption of ultrasound-guided polymer nanocarriers in tumor chemoradiotherapy and oxidation treatment

“…According to the damage level of neogrowth to the human body, the tumor is categorized as benign tumors and malignant tumors. The major differences between the two types of tumors include growth rate (benign tumors grow slowly, while malignant tumors grow fast), envelope metastasis (no envelope occurs in benign tumors, while envelope metastasis frequently occurs in malignant tumors), prognosis effect (the prognosis effect after benign tumor treatment is satisfactory, while malignant tumors adhere to peripheral tissues, and it usually recurs after treatment and even results in the death of patients) (2). Based on growth source, malignant tumors consist of cancer and sarcoma.…”

Highly sensitive detection of CYFRA21-1 with a SERS sensing platform based on the MBs enrichment strategy and antibody-DNA-mediated CHA amplification

“…In recent years, the incidence of malignant tumors has shown a rising trend, which seriously threatens the life and health of human beings. According to relevant data, the mortality rate of malignant tumors has increased by 83.1% compared with the mid-1970s, and the incidence rate of tumors has increased at a rate of 3%–5% per year ( Asahi et al, 2018 ; Li et al, 2020 ; Ohashi et al, 2022 ; Hosny et al, 2023 ). Laryngeal carcinoma (LC) is the second most common malignant tumor of the head and neck, and diseases such as atypical hyperplasia of the larynx, leukoplakia of the vocal cords, and papilloma are prone to transform into laryngeal cancer ( Wiegand et al, 2020 ; Li and Cheng, 2021 ; Sahin et al, 2022 ; Teng et al, 2022 ).…”

Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience

“…Pyogenic liver abscess (PLA) is a life-threatening disease with a mortality rate of 11-31% and almost 10,000 acute morbidities per year [ 1 ]. PLA is accompanied by risk factors and chronic diseases such as cardiovascular diseases, malignancies, diabetes mellitus, liver cirrhosis, cholangitis, urinary tract diseases, pneumonia, autoimmune diseases, and malnutrition [ 2 ]. However, up to 55% of patients with PLA have no known risk factors [ 3 ].…”