The Australian Twin ADHD Project: Current Status and Future Directions

Bennett, Kellie; Hay, David; Piek, Jan P.; Pearsall-Jones, Jillian G.; Lévy, Florence; Martin, Neilson

doi:10.1375/183242706779462804

Cited by 6 publications

(3 citation statements)

References 40 publications

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“…1). Our retention rate (17.9%) was lower than for other long-term follow-ups of similarly aged participants (43 to 80%) [11][12][13]. Many of these studies were designed for long-term follow-up, thus participants were aware of future follow-ups and had more regular assessments (e.g.…”

Section: Discussionmentioning

confidence: 80%

Re-engaging an inactive cohort of young adults: evaluating recruitment for the Kidskin Young Adult Myopia Study

Lingham

Mackey

Seed

et al. 2020

BMC Med Res Methodol

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Background: Recent changes in communication technologies, including increased reliance on mobile phones and the internet, may present challenges and/or opportunities to re-engaging inactive study cohorts. We evaluate our ability to recruit participants for the Kidskin Young Adult Myopia Study (KYAMS), a follow-up of the Kidskin Study. Methods: KYAMS participants were recruited from the Kidskin Study, a sun exposure-intervention study for 5-6 yearolds running from 1995 to 1999 with most recent follow-up in 2005. From 2015 to 2019, the KYAMS used mail-outs, phone calls and social media to contact Kidskin Study participants. Multivariable logistic regression was used to identify variables associated with successful contact of a Kidskin Study participant or family member and KYAMS participation. Results: Of 1695 eligible participants, 599 (35.5%) participants (or a family member) were contacted and 303 (17.9%) participated in the KYAMS. KYAMS participation was more likely in those who participated in the 2005 follow-up (odds ratio [OR] = 5.09, 95% confidence interval [CI]: 3.67-7.06) and had a mobile phone number on record (OR = 2.25, CI: 1.57-3.23). Of those contacted, participants who were the first point of contact (OR = 4.84, CI: 2.89-8.10) and who were contacted by letter in the first (OR = 6.53, CI: 3.35-12.75) or second (OR = 5.77, CI: 2.85-11.67) round were more likely to participate in the KYAMS, compared to contact by landline phone.

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Section: Discussionmentioning

confidence: 80%

Re-engaging an inactive cohort of young adults: evaluating recruitment for the Kidskin Young Adult Myopia Study

Lingham

Mackey

Seed

et al. 2020

BMC Med Res Methodol

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“…This study is part of the Australian Twin ADHD Project [48,49]. Using parental questionnaire, the Twin and Sibling Questionnaire, four categories of identical twins were investigated: (1) only one twin scored positive for DCD or ADHD (discordant co-twin con-trol design); (2) both twins scored positive for DCD or ADHD only; (3) both twins scored positive for both DCD+ADHD; (4) neither twin scored positive for DCD or ADHD.…”

Section: Participantsmentioning

confidence: 99%

A monozygotic twin design to investigate etiological factors for DCD and ADHD

et al. 2015

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The high level of comorbidity between Developmental Coordination Disorder (DCD) and Attention Deficit Hyperactivity Disorder (ADHD) suggests that these disorders may have a shared etiology. We used a co-twin control design to study monozygotic (MZ) twins concordant and discordant for DCD and ADHD. In a total of 922 sets of MZ twins, 866 sets were eligible. We found equal numbers of DCD concordant and discordant sets; more ADHD concordant than discordant sets; nine sets in which both twins met criteria for DCD+ADHD; 773 sets of twins did not meet criteria for either DCD or ADHD. The only significant sex difference between groups was for ADHD discordant sets, with more males than females. For DCD groups there were no significant sex differences, with slightly more girls than boys affected in both groups. There was a greater number of oxygen perfusion complications in DCD affected than unaffected twins, suggesting that, given equal numbers of DCD concordant and discordant sets and a similar number of DCD girls and boys, the role of pre- and perinatal environmental factors is stronger in the etiology of DCD than in ADHD. Factors such as placental difficulties and hypoxia have also been related to cerebral palsy, which suggests that DCD may fall on the upper end of a continuum of movement disorder that includes cerebral palsy. The results suggest different etiological pathways for DCD and ADHD. Second born twins were at greater risk for oxygen perfusion difficulties in sets concordant for DCD, ADHD, and unaffected for either.

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“…Over the past few decades, a number of welldesigned twin studies have been conducted on child and adolescent psychopathology (see Table 1), mainly in the United States and Europe (Bartels et al, 2007;Eaves et al, 1997;Hewitt et al, 1997;Iacono et al, 2006;Kaprio, 2006;Lemery-Chalfant et al, 2006;Lichtenstein et al, 2007;Neiderhiser et al, 2007;Trouton et al, 2002;van den Bree et al, 2007), with a few studies in Asia and Australia (Ando et al, 2006;Bennett et al, 2006;Huang et al, 2009;Hur Kuo et al, 2006). These studies have contributed significantly to the field by disentangling the intertwined roles of genetic and environmental factors in complex human traits, as well as by providing new information about the complex interplay between genes and the environment.…”

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confidence: 99%

The Beijing Twin Study (BeTwiSt): A Longitudinal Study of Child and Adolescent Development

Chen

Zhang

et al. 2012

Twin Res Hum Genet

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Rates of emotional and behavioral problems among children and adolescents in China are increasing and represent a major public health concern. To investigate the etiology of such problems, including the effects and interplay of genes and environment, the Beijing Twin Study (BeTwiSt) was established. A representative sample of adolescent twins in Beijing (N = 1,387 pairs of adolescent twins, mostly between the ages of 10 and 18 years) was recruited and assessed longitudinally. Data collection included the following: emotional and behavioral problems (e.g., depressive symptoms, anxiety, delinquency, drinking, and smoking); family, peer, and school environments; stress; social and academic competence; cognitive traits (e.g., emotion suppression, rumination, and effortful control); and saliva samples for DNA genotyping and sequencing. The combination of quantitative and molecular genetic approaches and the timeliness of the project, with the sample residing in a region with a rapidly changing economic and cultural climate, are particular strengths of this study. Findings from this study are expected to help understanding of the etiological mechanisms underlying child and adolescent normal and abnormal development in regions undergoing substantial social, cultural, and economic changes.

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The Australian Twin ADHD Project: Current Status and Future Directions

Cited by 6 publications

References 40 publications

Re-engaging an inactive cohort of young adults: evaluating recruitment for the Kidskin Young Adult Myopia Study

Re-engaging an inactive cohort of young adults: evaluating recruitment for the Kidskin Young Adult Myopia Study

A monozygotic twin design to investigate etiological factors for DCD and ADHD

The Beijing Twin Study (BeTwiSt): A Longitudinal Study of Child and Adolescent Development

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