The autoantibody expression against different source of oxidized low density lipoprotein in patients with acute myocardial infarction

Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population

“…The methodological approach to detecting antibodies to modified LDLs is very heterogeneous. For instance, the measurement of antibodies is influenced by the source of LDLs used in the ELISA, with the results varying depending on whether the LDLs come from persons with normal or high cholesterol levels (26). Another important source of variation is the subject's immune status, as levels of anti-oxidized LDL antibodies in patients with lupus erythematosus are very closely related to the degree of disease activity (27).…”

Adaptive immunity is related to coronary artery disease severity after acute coronary syndrome in subjects with metabolic syndrome

“…13 In the setting of coronary artery disease the presence of antibodies to different epitopes of oxidized lipids or peptides has been associated with acute coronary events. 34 Interestingly, in a murine model, human-derived IgG Fab antibody anti MDA-LDL blocked the uptake of oxLDL by macrophages in vivo, thus suggesting an important role in Table 2. Laboratory parameters of the study population at baseline and six weeks after an acute coronary syndrome.…”