The purpose of this work is to study the quality of the innovation-investment component of the international competitiveness of EU countries and Ukraine, to reveal the potential of innovation-investment activity in ensuring the effectiveness of the national economy, as well as to substantiate the priority vectors of leveling external shocks and promoting economic growth in Ukraine. The work evaluates the quality of the innovation and investment component of the international competitiveness of Ukraine and its close neighbors - the countries of the Visegrad Group (Poland, the Czech Republic, Hungary and Slovakia) using econometric analysis; a multifactor economic-mathematical model was built, which determines the strength of the connection between indicators of innovation and investment activity in Ukraine and the main macroeconomic indicator - GDP; the European practice of developing strategic programs to increase the competitiveness of the country's economy was studied; strategic innovation and investment initiatives of Ukraine are substantiated. In addition, the article made a significant theoretical and practical contribution to solving the outlined problems. The results of the study revealed the main problems of the innovation-investment component of Ukraine's international competitiveness, as well as highlighted the potential prospects for its improvement, taking into account advanced European practices.