This study examined the role of information, efficacy, and 3 stressors in predicting adjustment to organizational change. Participants were 589 government employees undergoing an 18-month process of regionalization. To examine if the predictor variables had long-term effects on adjustment, the authors assessed psychological well-being, client engagement, and job satisfaction again at a 2-year follow-up. At Time 1, there was evidence to suggest that information was indirectly related to psychological well-being, client engagement, and job satisfaction, via its positive relationship to efficacy. There also was evidence to suggest that efficacy was related to reduced stress appraisals, thereby heightening client engagement. Last, there was consistent support for the stress-buffering role of Time 1 self-efficacy in the prediction of Time 2 job satisfaction.Organizational change is typically activated by a relevant environmental shift that, once recognized by the organization, leads to an intentionally generated response (Porras & Silvers, 1991). In this respect, organizational change is intended to alter key organizational variables that then affect the members of the organization and their work-related behaviors, resulting in changes in a variety of organizational outcomes. Thus, organizational change can be viewed as a critical life event, which has the potential to evoke stress reactions and other negative consequences in employees. In this respect, employees are confronted with a unique set of workplace stressors resulting from a changing work environment. Because organizational change by its very nature is not linear, the most frequent psychological state resulting from organizational change is uncertainty (see