The bactericidal, fungicidal and sporicidal properties of hydrogen peroxide and peracetic acid

Abstract

The antimicrobial properties of aqueous solutions of peracetic acid and hydrogen peroxide have been compared. Peracetic acid exhibited excellent antimicrobial properties, especially under acidic conditions. Reductions by a factor of 10(6) in the numbers of vegetative bacteria are obtained within 1 min at 25 degrees C using a solution containing 1.3 mmol/l of peracetic acid. Rapid activity against bacterial spores and yeasts also occurs. Hydrogen peroxide is more effective as a sporicide than as a bactericide, with sporicidal action being obtained using a solution containing 0.88 mol/l. Bactericidal action is poor but hydrogen peroxide was bacteriostatic at concentrations above 0.15 mmol/l.

Anin vitroandin vivoevaluation of peroxyacetic acid as an alternative sanitizer for wine barrels

“…Baldry (1983) exposed S. cerevisiae to different concentrations of PAA, however different temperatures and pH were used (5.0, 6.5 and 8.0), versus our experiment, where pH was not a factor to control since only deionized water was used to prepare the PAA solutions that were added to the flasks (in vitro experiments) and where temperature was stable during the whole time of our experiment. Baldry (1983) found that the efficacy of PAA against two strains of S. cerevisiae decreases with increasing pH, since when alkalinity of the solution increases, peracetic acid is hydrolyzed to form acetic acid and hydrogen peroxide (Yuan et al, 1997). Accordingly, Baldry (1983) found that resistance among genera (particularly between Z. bailii and S. cerevisiae) is variable, this latter aspect also found in our experiments.…”

“…Baldry (1983) found that the efficacy of PAA against two strains of S. cerevisiae decreases with increasing pH, since when alkalinity of the solution increases, peracetic acid is hydrolyzed to form acetic acid and hydrogen peroxide (Yuan et al, 1997). Accordingly, Baldry (1983) found that resistance among genera (particularly between Z. bailii and S. cerevisiae) is variable, this latter aspect also found in our experiments. However, as we found resistance is also variable among strains.…”

“…This is not surprising, as disinfection, like other chemical processes, almost invariably takes place at a slower rate as the temperature falls (Baldry, 1983). Microbial spoilage of wine can occur at any stage of the vinification process due to nonSaccharomyces yeasts and lactic and acetic acid bacteria.…”

Comparison of anti-Aspergillus activity of Origanum vulgare L. essential oil and commercial biocide based on silver ions and hydrogen peroxide

“…Hydrogen peroxide is an oxidizing agent capable of transforming numerous organic molecules (Petri et al 2011). It has been documented that this compound exhibits antibacterial and antifungal properties (Baldry 1983). There are several studies concerning the antifungal activity of biocides based on silver ions and hydrogen peroxide (Tasić 2009, Abdel-Mageed et al 2012) but, to our knowledge, very few regarding Aspergillus species (e.g.…”

Comparação entre hipoclorito de sódio e ácido peracético na inativação de E. coli, colifagos e C. perfringens em água com elevada concentração de matéria orgânica

“…Devido às suas propriedades bactericidas, virucidas, fungicidas e esporicidas, seu uso como desinfetante de esgoto doméstico recebe cada vez mais atenção (Baldry, 1982;Baldry & French, 1989;Alasri et al, 1992;Sanchez-Ruiz et al, 1995;Gasi et al, 1995;Rajala-Mustonen et al, 1997;Block, 2001). Outras vantagens do ácido peracético como desinfetante de efluentes são: facilidade de implementação de tratamento (sem a necessidade de elevado investimento), largo espectro de atividade mesmo na presença de matéria orgânica heterogênea, ausência de residual ou subprodutos tóxicos e/ou mutagênicos, desnecessária descloração, baixa dependên-cia do pH e curto tempo de contato.…”