The bactericidal power of the stomach and some factors which influence it

Hanszen, A. H.

doi:10.1007/bf02999582

Cited by 10 publications

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“…The plantain banana is collected green and cooked as a food in many third world countries. There are a number of reports (Hanszen, 1934;Elliot & Heward, 1976;Sanyal et al, 1961) which associate the plantain banana with anti-ulcerogenic properties. In this paper we have examined dried unripe plantain banana for antiulcerogenic activity in the rat.…”

Section: Introductionmentioning

confidence: 99%

The anti‐ulcerogenic activity of the unripe plantain banana (Musa species)

Best

Lewis

Nasser

1984

British J Pharmacology

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IVarious preparations of dried unripe plantain banana were found to be anti-ulcerogenic against aspirin-induced ulceration in the rat and were effective both as a prophylactic treatment and in healing ulcers already induced by aspirin. Ripe fruit bananas were inactive. 2 The active factor(s) were water soluble and were concentrated by extraction to approximately three hundred times that in the dried banana powder. 3 The anti-ulcerogenic action of banana preparations appears to be due to their ability to stimulate the growth of gastric mucosa. 4 Aluminium hydroxide, cimetidine, prostaglandin E2, N6, 02-dibutyryl adenosine 3',5' cyclic monophosphate but not 5 -hydroxytryptamine were also anti-ulcerogenic when used prophylactically in rats but were ineffective in healing ulcers already formed by aspirin. These substances did not stimulate the growth of gastric mucosa.

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Section: Introductionmentioning

confidence: 99%