In this work, it was evaluated the wear resistance, hardness, and surface roughness values of resin-based composites that applied in dentistry as restorative materials. The resin composites were made from six types of resin matrixes (A, B, C, D, E, and F) and each one of them has contained different types and ratios of monomers as well as the inorganic nanofillers (SiO2, ZrO2, HA, and Al2O3). For each test, thirty specimens were prepared, which were classified into six groups depending on the types of the resin matrix and fillers used in the composites. The results prove that the nanocomposites that have the lowest rate of wear were the group E which was derived from the resin matrix of the group E that has monomers are (BIS-GMA, meth acrylamide, methacrylic acid, and 1-6 hexanediol methacrylate) with values range from 8.11 to 6.11 mm 3 /mm depending on the filler type material. All prepared composites resin materials (A to F) showed an increase in their hardness values as regards the reference, group D showed the highest hardness value followed by group B while group C was the lowest. The highest mean roughness was shown in groups A and F with 0.82 and 0.79 μm respectively, while the smoother surfaces among all groups were groups B and D which had significantly fewer roughness values of 0.16 and 0.19 μm respectively.