The Benefits of Platelet-Rich Fibrin in Promoting Post-Extraction Healing

Abstract

The aim of this study was to evaluate pain intensity and wound healing of the post-extraction sites after the use of Platelet-Rich Fibrin (PRF). 240 patients which needed difficult or multiple extractions were included in the study. The extractions were realized under local anesthesia, with piezotome and pliers. The patients were divided in two groups, the first group of 120 patients which benefited the application of PRF in the post-extraction alveoli, and the second group of 120 patients represented the control group (without application of PRF). A questionnaire was realized after a VAS analog scale and was used to quantify the post-intervention pain intensity in the postoperative four days. The assessment of the post-extraction sites healing period was performed clinically. According to the obtained results, the healing period of the post-extraction sites was shorter in the patients of first group (PRF), compared to the sites of control group patients. No postextractional healing complications occurred in the patients of first group/PRF. The study demonstrated the benefits of PRF insertion in post-intervention healing.

The Effect of Type 1 Atellocolagen in Association with Blood Self-derivatives in Alveolar Bone Augumentation

“…Moreover, the A-PRF used in this study is a blood cell concentrate, which contains a multitude of growth factors. It can be used as a mass for the augmentation of hard tissues both alone and combined with other bone augmentation materials [39]. The new A-PRF protocol, based on the low-speed centrifugation concept, is the most powerful concept as it combines the fibrin network, the growth factors from platelets and the white cell activity for only one goal: getting the more rapid and thorough vascularization of the local tissues [4,5,6].…”

Changes in Blood Elements Determined by Use of Articaine as a Local Anesthetic in Dental Medicine

“…The potential of the locoregional anesthesia represents the most physiological anesthesia method and has the widest indications in stomatology [1]. Among the requirements for acceptable dental material are included their quality and performances, their proper composition [2,3]. It is unanimously known that local anesthetics are the most frequently used substances in the dental office.…”