The Biological Activities of Cinnamon, Geranium and Lavender Essential Oils

Abstract

Acinetobacter sp. represent an important cause of nosocomial infections. Their resistance to some antibiotics, their ability to survive on inanimate surfaces in the hospital environment and their ability to produce biofilms contributes to their virulence. The aim of the study was to determine the antibacterial properties of cinnamon, lavender and geranium essential oils against bacteria of the genus Acinetobacter isolated from several clinical materials and from the hospital environment. A comprehensive evaluation of the susceptibility of Acinetobacter sp. clinical strains to recommended antibiotics was performed. The constituents of cinnamon, lavender and geranium essential oils were identified by GC-FID-MS analysis, and their Minimal Inhibitory Concentrations (MICs) against tested clinical strains were determined by the micro-dilution broth method. In addition, the effects of essential oils on the viability of human microvascular endothelial cells (HMEC-1) and glioblastoma cell line (T98G) were evaluated. Cinnamon bark oil was the most active against clinical and environmental strains of Acinetobacter baumannii with MIC values OPEN ACCESSMolecules 2014, 19 20930 ranging from 0.5 to 2.5 µL/mL. The MIC values for geranium oil were between 7.5 and 9.5 µL/mL, and between 10.5 and 13.0 µL/mL for lavender oil. These essential oils can be best employed in the fight against infections caused by bacteria from Acinetobacter genus as components of formulations for hygiene and disinfection of hospital environment.

The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains

“…Nevertheless, in this study the most effective combination of LEO and OCT decreased the MIC of LEO from 14.86 ± 3.96 mg/mL (1.49 ± 0.4%) to 1.29 ± 0.49 mg/mL (0.13 ± 0.05%). In our previous study, it was also observed that LEO derived from the same production batch exhibited low cytotoxic activity towards HMEC-1 and glioblastoma cell (T98G) lines [29]. IC 50 values of LEO against HMEC-1 and T98G lines were 5.15 µL/mL (4.5 mg/mL) and 2.27 µL/mL (1.99 mg/mL), respectively.…”

Designing monographs for Rosmarinus officinalis L. and Lavandula angustifolia L.: Two Lebanese species with significant medicinal potentials

“…According to the BP 2013, the major components of LEO are Linalool (20-45 %) and Linalyl acetate (25-47 %). Investigation of the composition of LEO from different regions of the world, have revealed that EOs of Lavender from different locations such as Greece, 22 Italy, 20,44 Poland, 45 Tunisia, 46 South Africa, 21 and Japan 47 were characterized by comparable levels Linalool and Linalyl acetate (2.67 ± 0.53 %) for L-SP (Table 8). Therefore, both samples produced EO in yields greater than the minimum limit of 1.3% specified for L. angustifolia.…”

An In Vitro Study on the Antimicrobial Properties of Essential Oil Modified Resin Composite against Oral Pathogens

“…This study used the following ten commercially available essential oils (dr Beta, Pollena Aroma, Nowy Dwór Mazowiecki, Poland): anise, cinnamon, citronella, clove, geranium, lavender, limette, mint, rosemary and thyme. The composition of tested EOs was presented in Table 1 , based on data obtained from previous studies analyzing the EOs’ composition by gas chromatography with flame-ionization and mass spectroscopic detection (GC-FID-MS) [ 46 , 47 , 48 , 49 , 50 , 51 , 52 ] or data from European Pharmacopoeia [ 53 ].…”