The biological transformation of industrial manufacturing – Technologies, status and scenarios for a sustainable future of the German manufacturing industry

Miehe, Robert; Bauernhansl, Thomas; Beckett, Marc; Brecher, Christian; Demmer, Axel; Drossel, Welf Guntram; Elfert, P.; Full, Johannes; Hellmich, Arvid; Hinxlage, J.; Horbelt, J.; Jutz, G.; Krieg, Stefan W.; Maufroy, Christophe; Noack, Marian; Sauer, Alexander; Schließmann, Ursula; Scholz, Patrick; Schwarz, Oliver; Hompel, Michael ten; Wrycza, P.; Wolperdinger, Markus

doi:10.1016/j.jmsy.2019.11.006

Cited by 54 publications

(25 citation statements)

References 69 publications

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“…Consequently, a biointelligent system requires the implementation of an interface between biological and technical components. In addition to the identification of biosensors as key enabling technologies, so-called biology–technology interfaces (BTI) were identified as one of the core areas of future research [ 6 ]. The generic concept of a BTI comprises the recording and processing of information as well as control actions derived from it.…”

Section: Discussionmentioning

confidence: 99%

“…As such, it describes an interdisciplinary innovation pathway that seeks to increase the use of biological materials, structures, processes and organisms in technical systems through intensive collaboration and combination of production, information and biotechnology [ 2 , 5 ]. According to Miehe et al [ 6 ], the development of the biological transformation can be divided into three modes. The first mode, bioinspiration, describes the transfer of evolutionarily optimized biological principles and processes to technology.…”

Section: Introductionmentioning

confidence: 99%

“…The third development mode involves the interaction between technical, biological and information systems. This form of systemic interaction enables the creation of self-regulating value-added systems and products, which are summarized under the term biointelligence [ 6 ]. A system or product is considered to be biointelligent if there is a real time exchange of information between biological and technical components [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

“…As part of a comprehensive pilot survey commissioned by the German government with regard to the biological transformation, biosensors were identified as one of the key enabling technologies. In this course, among others, odor-detecting biosensors were presented as promising examples [ 6 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

et al. 2021

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The technological advantages that biosensors have over conventional technical sensors for odor detection and the role they play in the biological transformation have not yet been comprehensively analyzed. However, this is necessary for assessing their suitability for specific fields of application as well as their improvement and development goals. An overview of biological basics of olfactory systems is given and different odor sensor technologies are described and classified in this paper. Specific market potentials of biosensors for odor detection are identified by applying a tailored methodology that enables the derivation and systematic comparison of both the performance profiles of biosensors as well as the requirement profiles for various application fields. Therefore, the fulfillment of defined requirements is evaluated for biosensors by means of 16 selected technical criteria in order to determine a specific performance profile. Further, a selection of application fields, namely healthcare, food industry, agriculture, cosmetics, safety applications, environmental monitoring for odor detection sensors is derived to compare the importance of the criteria for each of the fields, leading to market-specific requirement profiles. The analysis reveals that the requirement criteria considered to be the most important ones across all application fields are high specificity, high selectivity, high repeat accuracy, high resolution, high accuracy, and high sensitivity. All these criteria, except for the repeat accuracy, can potentially be better met by biosensors than by technical sensors, according to the results obtained. Therefore, biosensor technology in general has a high application potential for all the areas of application under consideration. Health and safety applications especially are considered to have high potential for biosensors due to their correspondence between requirement and performance profiles. Special attention is paid to new areas of application that require multi-sensing capability. Application scenarios for multi-sensing biosensors are therefore derived. Moreover, the role of biosensors within the biological transformation is discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

et al. 2021

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“…Sustainability is increasingly becoming the inherent challenge for future industrial production. [ 1 ] Since the beginning of industrialization and the exponential population growth associated with it, the extraction of resources and the amount of greenhouse gases in the atmosphere have multiplied. In the last 30 years, global resource consumption has doubled, leading to an aggregated growth rate of 118%.…”

Section: Introductionmentioning

confidence: 99%

Sustainable production and the role of digital twins–Basic reflections and perspectives

Miehe

Waltersmann

Sauer

et al. 2021

J Adv Manuf & Process

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Sustainable production is essential for the future of the global economy. Despite the publication of its baseline vision over 30 years ago and the resulting diversity of interpretations and subdisciplines in engineering and social sciences, the progress of the approach in industrial practice remains marginal. This is mainly due to the fact that the discipline has not yet succeeded to realize the magnitude of the rethinking necessary of its very own perception as a whole. Existing definitions of sustainable production presented to date are thus only partly consistently derived from the baseline concept. Meanwhile, digitalization provides an increasing number of technologies that offer a new perspective on sustainable production. This especially applies to the concept of digital twins. Recent studies, thus, address their role in the context of sustainable production by analyzing its contribution to existing sustainability related methods as well as technical challenges on a microeconomic level (bottom‐up approach). Although these approaches provide concrete requirements for technical deployment, it is highly questionable how they will contribute to sustainable production as a whole. In this paper, we choose a top‐down approach to discuss the role of digital twins in the context of sustainable production. Based on fundamental reflections on the baseline concept of sustainability, we advocate a reorientation of production within the framework of planetary boundaries. Thereupon, we discuss the role of digital twins and digital threads and provide a number of requirements that future R&D needs to address for a future sustainability‐oriented data‐driven monitoring and regulation of production.

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Materials Inspired by Living Functions

Kostiainen,

Priimagi,

Timonen

et al. 2024

Adv Funct Materials

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Engineering or mimicking living materials found in nature has the potential to transform the use of materials. Unlike classic synthetic materials which are typically optimized for static properties, economics, and recently also for sustainability, materials of life are dynamic, feedback‐controlled, evolving, and adaptive. Although synthetic materials do not typically exhibit such complicated functionalities, researchers are increasingly challenging this viewpoint and expanding material concepts toward dynamic systems inspired by selected life‐like functions. Herein, it is suggested that such materials can be approached from two perspectives: through engineering of biological organisms and their functions to provide the basis for new materials, or by producing synthetic materials with selected rudimentary life‐inspired functions. Current advances are discussed from the perspectives of (i) new material features based on built‐in memory and associative learning, (ii) emergent structures and self‐regulated designs using non‐equilibrium systems, and (iii) interfacing living and non‐living systems in the form of cellular community control and growth to open new routes for material fabrication. Strategies combining (i)–(iii) provide materials with increasingly life‐inspired responses and potential for applications in interactive autonomous devices, helping to realize next‐generation sensors, autonomous and interactive soft robots, and external control over the bioproduction of self‐organizing structural materials.

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The biological transformation of industrial manufacturing – Technologies, status and scenarios for a sustainable future of the German manufacturing industry

Cited by 54 publications

References 69 publications

Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

Sustainable production and the role of digital twins–Basic reflections and perspectives

Materials Inspired by Living Functions

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