The Budd-Chiari Syndrome in Sarcoidosis

Budd-Chiari Syndrome: Some Pathologic-Anatomic Aspects

“…12-14 In addition, malignant neoplastic tissue masses, augmented lymph nodes, cicatrizations, abdominal traumas, x-ray radiation, diseases of the gastrointestinal tract, and rheumatic angiitis must be considered as possible causes of venous occlusion. [15][16][17][18][19][20][21][22][23] Hepatic vein thrombosis may also be both a result of a precedent thrombosis of the inferior vena cava and a cause of the latter by a hypertrophy of the quadrate lobe of the liver with consecutive compression of the vena cava. [24][25][26] Finally, malformations, namely congenital septal-shaped membranes at the junction of the hepatic veins into the inferior vena cava may also lead to the obstruction of the venous outflow.…”

Unusual presentation of sarcoidosis in a child

“…The exact mechanism for Budd-Chiari syndrome associated with hepatic sarcoidosis is unclear. It has been postulated that extrinsic factors such as granulomas that restrict the venous flow are responsible for the development of Budd-Chiari syndrome as was present in our case [10,11]. In the normal course of the disease, granulomas are gradually replaced by fibrosis.…”

Extrapulmonary sarcoidosis of liver and pancreas: A case report and review of literature

“…Since granulomas in the liver are small and preferably located in the portal space, clinical hepatic manifestations are rare. Those may include jaundice and chronic cholestasis [6,[35][36][37][38] , portal hypertension [39,40] , or Budd Chiari syndrome [41,42] . Intrahepatic cholestasis can resemble primary biliary cirrhosis [43] or sclerosing cholangitis [44] .…”