Unusual presentation of sarcoidosis in a child

Krishnamoorthy, Gowri; Ray, Gautham; Agarwal, Indira; Kumar, Sathish

doi:10.1007/s00296-011-1909-8

Cited by 8 publications

(6 citation statements)

References 10 publications

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“…12 On the other hand, treatment of BCS is better codified, based on anticoagulation therapy and treatment of the underlying condition; in case of failure, transjugular intrahepatic portosystemic shunt (TIPS) insertion and liver transplantation should be considered. 14 Regarding previous reported cases of BCS associated with sarcoidosis: 3 patients were treated with corticosteroids for liver involvement 5 , 7 , 8 associated with anticoagulation in one case 8 while 3 patients had liver transplantation (after TIPS failure for one) 3 , 6 , 9 and the 2 former had surgical portosystemic shunt. 10 , 11 Thus, this is the second case of BCS complicating hepatic sarcoidosis treated with anticoagulation and corticosteroids.…”

Section: Discussionmentioning

confidence: 98%

Budd-Chiari Syndrome: An Unusual Presentation of Multisystemic Sarcoidosis

Ennaifer

Bacha

Romdhane

et al. 2015

Clinics and Practice

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Sarcoidosis is a multisystem granulomatous disease of unknown origin. All organs may be affected. Liver involvement is common but it is rarely symptomatic. Only a few cases of Budd-Chiari syndrome (BCS) secondary to a hepatic sarcoidosis have been described so far. We describe a case of multisystemic sarcoidosis presenting with BCS. A 42-year old female was referred to our department for chronic and anicteric cholestasis. Laboratory and imaging investigations disclosed features of chronic BCS associated with multisystemic sarcoidosis. The positive diagnosis was based on microscopic features, which showed hepatic, gastric and cutaneous non-caseating granulomas. Screening for an underlying thrombophilic disorder was negative. The diagnosis of BCS complicating hepatic sarcoidosis was the most likely. She was put on corticosteroids and anticoagulation therapy. To our knowledge, few cases of sarcoidosis-related BCS have been reported in the literature. In addition to being an uncommon presentation of sarcoidosis, this case illustrates the importance of recognizing an unusual cause of BCS and its therapeutic difficulties.

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Section: Discussionmentioning

confidence: 98%

Budd-Chiari Syndrome: An Unusual Presentation of Multisystemic Sarcoidosis

Ennaifer

Bacha

Romdhane

et al. 2015

Clinics and Practice

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“…In their study, Chau et al [14] found periportal hyperechogenicity in 15 patients (30%) who presented with recurrent pyogenic cholangitis. Finally, hyperechogenicity was also recorded in patients with dengue fever [15], chikungunya virus-induced acute arthritis [16], leptospirosis [17], and febrile attacks of sarcoidosis [18].…”

Section: Discussionmentioning

confidence: 99%

Transient periportal hyperechogenicity in feverish patients: a novel ultrasonographic finding

2019

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Purpose Periportal hyperechogenicity has been recorded in many inflammatory and infectious diseases, including viral hepatitis, inflammatory bowel diseases, toxic shock syndrome of staphylococcus infection, typhoid fever, and schistosomiasis. We aimed to evaluate the echogenicity of the portal tracts of the liver by abdominal ultrasound imaging in patients with fever irrespective of the cause. Methods Abdominal ultrasound examination was performed in 277 consecutive patients presented with fever at their first visit and repeated 2 weeks later after their recovery. Results Transient periportal hyperechogenicity was present in 39% (108 patients) of the feverish patients studied irrespective of the cause of the fever. Conclusion Transient periportal hyperechogenicity is a frequent ultrasonographic finding in feverish patients irrespective of the cause of fever, and hence should not be misdiagnosed as liver disease or chronic periportal fibrosis unless the hyperechogenicity persists after recovery from the febrile or inflammatory condition.

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“…Furthermore, 2 pediatric cases of BCS were described to be associated with hepatic sarcoidosis; 1 was treated with corticosteroids, whereas the other was initially treated with a TIPS, complicated by recurrent thrombosis which eventually required liver transplantation. 16,17…”

Section: Discussionmentioning

confidence: 99%

Budd-Chiari Syndrome in a Patient With Simultaneous Diagnosis of Hepatic Sarcoidosis and Nodular Regenerative Hyperplasia

et al. 2019

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Budd-Chiari syndrome (BCS) is a rare vascular disorder characterized by an obstruction of the hepatic venous outflow. Nodular regenerative hyperplasia (NRH) may develop as a result of an underlying autoimmune disease such as hepatic sarcoidosis. Only a few case reports have described cases with either NRH or hepatic sarcoidosis associated with BCS. We present a 42-year-old man presenting with BCS and signs of portal hypertension who was found to have an underlying pathological diagnosis of both hepatic sarcoidosis and NRH and who was successfully treated with a transjugular intrahepatic portosystemic shunt.

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Unusual presentation of sarcoidosis in a child

Cited by 8 publications

References 10 publications

Budd-Chiari Syndrome: An Unusual Presentation of Multisystemic Sarcoidosis

Budd-Chiari Syndrome: An Unusual Presentation of Multisystemic Sarcoidosis

Transient periportal hyperechogenicity in feverish patients: a novel ultrasonographic finding

Budd-Chiari Syndrome in a Patient With Simultaneous Diagnosis of Hepatic Sarcoidosis and Nodular Regenerative Hyperplasia

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