2007
DOI: 10.1007/s00431-007-0529-5
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The burden of respiratory viral disease in hospitalized children in Paris

Abstract: A virus was identified in 464 out of 1,212 patients, 8 days to 16 years of age, who were admitted to the hospital in Paris during a 3 year period. Respiratory syncytial virus (RSV) was found in 428 patients, 74% were younger than 6 months with bronchiolitis, and 6% were older than 2 years. RSV was the first virus isolated in all patients and in those with pneumonia or asthma. The low number of admissions due to parainfluenzae viruses is characteristic of this area compared to other countries.

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Cited by 11 publications
(5 citation statements)
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“…In our retrospective study, we analysed demographic, seasonal and epidemiological factors, as well as clinical manifestations of both RSV and non-RSV bronchiolitis in infants and children under the age of two years, with the course of the disease severe enough to require hospitalisation. The aetiology of bronchiolitis in the children studied was RSV infection in only 33% of them, in contrast to other studies reporting RSV aetiology in as many as [1,10], and ranging widely from 17.5% [12] to 80.8% [13] in epidemiological studies that included patients aged from one to 16 years. The practice in our hospital, on admission, is to perform a nasopharyngeal aspirate, and an immunofluorescent test is routinely performed in children to define the aetiology of ALRI; however, its sensitivity and specificity are a matter of debate [14,15] and may be, at least in part, responsible for false negative results.…”
Section: Discussioncontrasting
confidence: 72%
“…In our retrospective study, we analysed demographic, seasonal and epidemiological factors, as well as clinical manifestations of both RSV and non-RSV bronchiolitis in infants and children under the age of two years, with the course of the disease severe enough to require hospitalisation. The aetiology of bronchiolitis in the children studied was RSV infection in only 33% of them, in contrast to other studies reporting RSV aetiology in as many as [1,10], and ranging widely from 17.5% [12] to 80.8% [13] in epidemiological studies that included patients aged from one to 16 years. The practice in our hospital, on admission, is to perform a nasopharyngeal aspirate, and an immunofluorescent test is routinely performed in children to define the aetiology of ALRI; however, its sensitivity and specificity are a matter of debate [14,15] and may be, at least in part, responsible for false negative results.…”
Section: Discussioncontrasting
confidence: 72%
“…Les infections respiratoires sont fréquentes chez l'enfant, et la plupart d'entre elles sont d'origine virale [1,2]. Dans les pays à climat tempéré, elles surviennent principalement en hiver [2].…”
Section: Introductionunclassified
“…RSV is one of the most important causes of infant mortality and hospitalization worldwide and causes more cases of viral pneumonia in infants than any other virus [3,4,5]. It is highly transmissible, spreading through communities rapidly and infecting most of the population by the age of one [6].…”
Section: Introductionmentioning
confidence: 99%