Let k be a separably closed field. Let G be a reductive algebraic k-group. We study Serre's notion of complete reducibility of subgroups of G over k. In particular, using the recently proved center conjecture of Tits, we show that the centralizer of aWe present examples where the number of overgroups of irreducible subgroups and the number of G(k)-conjugacy classes of k-anisotropic unipotent elements are infinite. much is known about complete reducibility over an arbitrary k except a few general results and important examples in [3], [6], [7, Sec. 7], [8], [38], [36, Thm. 1.8], [37, Sec. 4]. Let k s be a separable closure of k. Recall that if k is perfect, we have k s = k. The following result [6, Thm. 1.1] shows that if k is perfect and G is connected, most results in this paper just reduce to the algebraically closed case. Proposition 1.2. Let k be a field. Let G be connected. Then a k-subgroup H of G is G-cr over k if and only if H is G-cr over k s .