The Characteristic of Bone Marrow Stem Cells of Patients With the Complicated Diabetes

Abstract

Introduction. An increase in patients with diabetes and a large number of amputations of limbs make the search for new treatments for these patients. Materials and methods. The study included 17 patients with complicated forms of diabetes. Patients were studied in the bone marrow immediately after surgery - the amputation of the limb. The number of hematopoietic stem cells and mesenchymal stem cells using specific markers were determined in the laboratory. The immunohistochemical characteristics of bone marrow were carried out for all samples. Results and conclusion. The obtained results indicate the biological value of bone marrow removed with amputation of the lower limb of the patient with complicated diabetes mellitus. The ease of obtaining bone marrow makes the procedure approachable in surgical practice. The presence of hematopoietic and mesenchymal stem cells provides the opportunity to use them in autologous cell therapy for patient.

Bone Marrow of Tubular Bones in the Oncological Process

“…For now, we 're still losing cancer in the fight. In surgical practice, they are periodically forced to amputate the lower limb because it is impossible to preserve it (Nikolaeva et al, 2017). High amputations lead to limited social adaptation of patients (Nikolaeva et al, 2015), significantly reduce the life expectancy of patients as a result of damage to the contralateral limb and the addition of various complications (Sisla et al, 2011).…”